极低出生体重儿脑损伤与脑容量改变研究进展

被引：6

作者：

胡传来 ^{[1
]}

孙莹 ^{[1
]}

潘家华 ^{[2
]}

机构：

[1] 安徽医科大学公共卫生学院

[2] 安徽医科大学附属省立医院儿科

来源：

中华全科医学 | 2009年 / 7卷 / 03期

关键词：

婴儿,极低出生体重; 脑损伤; 脑容量; 磁共振成像;

D O I：

10.16766/j.cnki.issn.1674-4152.2009.03.049

中图分类号：

R722 [新生儿、早产儿疾病];

学科分类号：

100202 [儿科学];

摘要：

20世纪60年代以来,伴随着新生儿重症监护技术的推广,极低出生体重儿的生存率得到了显著性提高,外表无严重残障的极低出生体重儿也达到了80%～90%。然而,神经系统的高级功能发育障碍依然存在,极低出生体重儿学龄期认知功能和学习成绩明显低于正常出生体重儿童,即使在智力正常和神经功能缺损不明显的低出生体重儿童中学习障碍也很常见,且这种学习障碍一般要持续到青春期。研究显示,极低出生体重的儿童至青春期甚至成年期仍可见大脑多个部位存在结构性异常,然而,它与脑损伤及脑容量改变的关系尚未明确。

引用

页码：299 / 302

页数：4

共 11 条

[1]

Low-birth-weight adolescents: Psychiatric symptoms and cerebral MRI abnormalities [J].

Indredavik, MS ;

Skranes, JS ;

Vik, T ;

Heyerdahl, S ;

Romundstad, P ;

Myhr, GE ;

Brubakk, AM .

PEDIATRIC NEUROLOGY, 2005, 33 (04) :259-266

[2]

Cerebral MRI findings in very-low-birth-weight and small-for-gestational-age children at 15 years of age [J].

Skranes, JS ;

Martinussen, M ;

Smevik, O ;

Myhr, G ;

Indredavik, M ;

Vik, T ;

Brubakk, AM .

PEDIATRIC RADIOLOGY, 2005, 35 (08) :758-765

[3]

Defining the nature of the cerebral abnormalities in the premature infant: A qualitative magnetic resonance imaging study [J].

Inder, TE ;

Wells, SJ ;

Mogridge, NB ;

Spencer, C ;

Volpe, JJ .

JOURNAL OF PEDIATRICS, 2003, 143 (02) :171-179

[4]

Catch-up growth of head circumference of very low birth weight, small for gestational age preterm infants and mental development to adulthood [J].

Brandt, I ;

Sticker, EJ ;

Lentze, MJ .

JOURNAL OF PEDIATRICS, 2003, 142 (05) :463-468

[5]

Regional and progressive thinning of the cortical ribbon in Huntington's disease [J].

Rosas, HD ;

Liu, AK ;

Hersch, S ;

Glessner, M ;

Ferrante, RJ ;

Salat, DH ;

van der Kouwe, A ;

Jenkins, BG ;

Dale, AM ;

Fischl, B .

NEUROLOGY, 2002, 58 (05) :695-701

[6]

Behavioural problems in children who weigh 1000 g or less at birth in four countries [J].

Hille, ETM ;

den Ouden, AL ;

Saigal, S ;

Wolke, D ;

Lambert, M ;

Whitaker, A ;

Pinto-Martin, JA ;

Hoult, L ;

Meyer, R ;

Feldman, JF ;

Verloove-Vanhorick, SP ;

Paneth, N .

LANCET, 2001, 357 (9269) :1641-1643

[7]

Magnetic resonance and cranial ultrasound characteristics of periventricular white matter abnormalities in newborn infants [J].

Childs, AM ;

Cornette, L ;

Ramenghi, LA ;

Tanner, SF ;

Arthur, RJ ;

Martinez, D ;

Levene, MI .

CLINICAL RADIOLOGY, 2001, 56 (08) :647-655

[8]

Neurodevelopmental status at 1 year predicts neuropsychiatric outcome at 14–15 years of age in very preterm infants.[J].S Roth;J Wyatt;J Baudin;J Townsend;L Rifkin;T Rushe;C Amiel-Tison;A.L Stewart.Early Human Development.2001, 2

[9]

Cognitive and motor function and the size of the cerebellum in adolescents born very pre-term.[J].Matthew Allin;Hideo Matsumoto;Alastair M. Santhouse;Chiara Nosarti;Mazin H. S. AlAsady;Ann L. Stewart;Larry Rifkin.Brain.2001,

[10]

Brain structure and neurocognitive and behavioural function in adolescents who were born very preterm [J].

Stewart, AL ;

Rifkin, L ;

Amess, PN ;

Kirkbride, V ;

Townsend, JP ;

Miller, DH ;

Lewis, SW ;

Kingsley, DPE ;

Moseley, IF ;

Foster, O ;

Murray, RM .

LANCET, 1999, 353 (9165) :1653-1657

← 1 2 →