脑缺血再灌注损伤与自噬关系的研究进展

被引：9

作者：

侯杨

冯娟

机构：

[1] 中国医科大学附属盛京医院神经内科

来源：

中风与神经疾病杂志 | 2018年 / 35卷 / 03期

关键词：

D O I：

10.19845/j.cnki.zfysjjbzz.2018.03.027

中图分类号：

R743 [脑血管疾病];

学科分类号：

100204 [神经病学];

摘要：

<正>缺血性脑卒中是神经系统中最为高发的疾病之一,且在脑血流再灌注后会引发一系列的病理反应从而造成更为严重的二次损伤。自噬是一种复杂的细胞代谢过程,在不同因素刺激下促使溶酶体吞噬细胞器等胞质组分,广泛参与机体的生理及病理过程,它是异于坏死和凋亡的并可作为细胞自我防御的代谢过程。脑缺血再灌注损伤(cerebral ischemiareperfusion injury,CIRI)可激活受损后的神经细胞发生自噬,自噬又与CIRI的发展紧密相关。本文对自噬的形成过程及

引用

页码：272 / 274

页数：3

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