同型半胱氨酸与脑血管疾病

被引：9

作者：

邓兵梅

机构：

[1] 广州医学院第二附属医院神经科学研究所

来源：

国外医学神经病学神经外科学分册 | 2003年 / 05期

关键词：

同型半胱氨酸; 高同型半胱氨酸血症; 动脉粥样硬化; 脑血管疾病; 基因;

D O I：

10.16636/j.cnki.jinn.2003.05.017

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

摘要：

高Hcy血症是脑血管疾病的独立危险因素,其机制可能与其诱导动脉粥样硬化有关。Hcy代谢相关基因多态性如MTHFR C677T、CBS T833C、MS D919G、MTRR A66G突变可能通过影响酶的活性导致高Hcy血症,进而与脑血管疾病相关联。补充叶酸、VitB6和VitB12可以治疗和预防高Hcy血症,但其远期效果有待进一步研究。

引用

页码：454 / 457

页数：4

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