基于NF-κB信号通路的中药抗溃疡性结肠炎研究进展

被引：73

作者：

王鹏程 ^{[1
]}

赵珊 ^{[1
]}

冯健 ^{[1
]}

赵宏 ^{[1
,2
]}

王秋红 ^{[1
]}

匡海学 ^{[1
]}

机构：

[1] 黑龙江中医药大学中药学教育部重点实验室

[2] 佳木斯大学药学院

来源：

中草药 | 2015年 / 46卷 / 10期

关键词：

NF-κB信号通路; 溃疡性结肠炎; 中药复方; 单味药材; 活性成分;

D O I：

暂无

中图分类号：

R285.5 [中药实验药理];

学科分类号：

100806 [中药药理学];

摘要：

溃疡性结肠炎是一种慢性、非特异性肠病,其发病机制尚不明确。目前的治疗以氨基水杨酸、类固醇激素与免疫抑制剂3类药物为主,但是无法有效的防治,不可长期使用。近年来,大量研究以中药复方、单味药或者活性成分为研究对象,以期开发出治疗、预防溃疡性结肠炎的新型药物。就NF-κB信号通路在溃疡性结肠炎中的作用及以NF-κB通路中相关蛋白和酶为靶点的中药抗溃疡性结肠炎的研究进展进行综述。

引用

页码：1556 / 1561

页数：6

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