培哚普利、氨氯地平降压治疗对原发性高血压患者大动脉弹性的影响

被引：2

作者：

薄小萍

陈茂华

吴小庆

李晓燕

张常莹

陆卫红

鲍小京

机构：

[1] 无锡市人民医院心脏病科

来源：

江苏医药 | 2011年 / 37卷 / 19期

关键词：

高血压病; 培哚普利; 氨氯地平; 动脉弹性;

D O I：

10.19460/j.cnki.0253-3685.2011.19.023

中图分类号：

R544.1 [高血压];

学科分类号：

1002 ; 100201 ;

摘要：

目的比较培哚普利、氨氯地平改善原发性高血压患者动脉弹性的作用。方法 78例轻中度原发性高血压患者随机均分成培哚普利组和氨氯地平组,以血压<140/90 mm Hg为降压达标,检测用药前和降压达标后4、12周的颈股脉搏波传导速度(cfPWV)。结果与治疗前比较,培哚普利组和氨氯地平组治疗后4、12周的cfPWV均明显下降[(12.9±2.3)m/s vs.(11.1±2.1)m/s、(9.6±1.7)m/s和(13.3±2.6)m/s vs.(11.4±2.2)m/s、(9.4±1.6)m/s](P<0.01)。结论运用培哚普利、氨氯地平降压达标,均能改善原发性高血压患者大动脉弹性。

引用

页码：2296 / 2298

页数：3

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