基于“骨肉不相亲”理论骨与骨骼肌关系的探讨

被引：38

作者：

戚晓楠 ^{[1
]}

姚啸生 ^{[2
]}

郑洪新 ^{[1
]}

任璐 ^{[1
]}

机构：

[1] 辽宁中医药大学

[2] 辽宁中医药大学附属医院

来源：

中国骨质疏松杂志 | 2019年 / 25卷 / 10期

基金：

国家重点研发计划;

关键词：

中医中药; 骨肉不相亲; 骨骼; 骨骼肌; 骨质疏松; 肌肉减少症;

D O I：

暂无

中图分类号：

R580 []; R685 [肌肉疾病及损伤];

学科分类号：

100220 [骨科学];

摘要：

骨质疏松症和肌肉减少症是老龄化社会常见的增龄性肌骨疾病。现代研究提示,骨与骨骼肌作为共同的功能单位参与了增龄性肌骨疾病的病理过程,从生物力学机制、能量代谢、内分泌、细胞、基因和信号通路等多方面存在相互关联。因此,对骨与骨骼肌关系的研究将有助于预防和治疗此类疾病。中医对骨与骨骼肌关系多从"脾肾"关系来认识,其中,"骨肉不相亲"理论是这种认识的高度概括。现代研究从多维度验证了"骨肉不相亲"理论的合理性。基于"骨肉不相亲"理论和骨与骨骼肌关系的现代研究成果,笔者从生物力学机制、内分泌、能量代谢、基因和信号通路等方面讨论骨与骨骼肌的关系,为骨质疏松症和肌肉减少症等增龄性肌骨疾病的精准防治提供新的思路和有效药物。

引用

页码：1487 / 1492

页数：6

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