哮喘动物模型的研究现状

被引:7
作者
戴继宏
谭毅
符州
机构
[1] 重庆医科大学儿童医院!重庆
[2] 重庆医科大学实验动物中心
关键词
哮喘; 动物/实验;
D O I
暂无
中图分类号
R-332 [医用实验动物学];
学科分类号
1001 ;
摘要
通过对近年来国外哮喘实验研究文献进行总结 ,从制备哮喘模型常用动物的选择、制备模型的要素到哮喘模型的研究应用等方面进行综合分析 ,指出各种常用哮喘实验动物在哮喘研究中的适用范围 ,目前豚鼠仍是常用的哮喘实验动物 ,但是大小鼠的应用也日渐增多。在文献数据等结论基础上评价各种制备方法之特点 ,对改进方法进行详细描述及评价。最后对动物模型在哮喘发病机制中的应用 ,尤其是免疫发病机制中细胞因子与哮喘动物模型的关系进行了较为详细的阐述分析。指出应根据不同的哮喘临床类型及研究目的选用相应的方法对实验动物进行致敏及激发
引用
收藏
页码:40 / 44
页数:5
相关论文
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