急性肺损伤发生机制的研究进展

被引:2
作者
唐镍 [1 ]
曹玥 [2 ]
黄英 [2 ]
机构
[1] 四川大学
[2] 四川大学华西基础医学与法医学院病理生理学教研室
关键词
急性肺损伤; 中性粒细胞; 血管内皮细胞; 肺泡巨噬细胞;
D O I
暂无
中图分类号
R563.8 [呼吸衰竭];
学科分类号
1002 ; 100201 ;
摘要
<正>急性肺损伤(acute lung injury,ALI)是指由严重感染、创伤等不同病因所致的肺泡毛细血管内皮细胞、肺泡上皮细胞和肺间质的急性弥漫性损害,其本质是肺部多种炎性细胞如中性粒细胞(PMN)、肺泡巨噬细胞(alveolar macrophage,AM)等所介导的肺部炎性反应及失控的炎性反应所致的肺泡-毛细血管膜损伤。本文就PMN、AM、血管内皮细胞(endothelial cell,EC)及肺组织核转录因子(NF-кB)在ALI发生机制的研究进
引用
收藏
页码:398 / 400
页数:3
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