过敏性紫癜的免疫学异常

被引：38

作者：

张琴

机构：

[1] 安徽医科大学附属第一医院儿科

来源：

国际免疫学杂志 | 2007年 / 01期

关键词：

紫癜; 过敏性; 免疫学异常;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

过敏性紫癜(HSP)是与免疫反应有关的系统性血管炎,其免疫学机制主要为体液免疫异常,IgA的作用尤其受到重视。T细胞功能紊乱和多种促炎症因子失调,并且其免疫复合物激活补体发挥作用。对该病免疫遗传方面的研究表明HSP患者具有多种基因多态性,感染可能是免疫学异常的触发因素,因此HSP发病并非单一因素作用的结果,从免疫反应异常、遗传因素、发病诱因等多方面综合分析才能深入理解HSP的发病机理。

引用

页码：61 / 64 +4

共 9 条

[1]

Analysis of a uteroglobin gene polymorphism in childhood Henoch–Schonlein purpura[J] . Eli M. Eisenstein,Moonsuk Choi.Pediatric Nephrology . 2006 (6)

[2]

The role of tumor necrosis factor-α in Henoch-Sch?nlein purpura[J] . Tae-Sun Ha.Pediatric Nephrology . 2005 (2)

[3]

The significance of IgA class of antineutrophil cytoplasmic antibodies (ANCA) in childhood Henoch–Sch?nlein purpura[J] . Fatih Ozaltin,Aysin Bakkaloglu,Seza Ozen,Rezan Topaloglu,Umut Kavak,Mukaddes Kalyoncu,Nesrin Besbas.Clinical Rheumatology . 2004 (5)

[4]

The role of apoptosis in childhood Henoch–Schonlein purpura[J] . F. Ozaltin,N. Besbas,D. Uckan,M. Tuncer,R. Topaloglu,S. Ozen,U. Saatci,A. Bakkaloglu.Clinical Rheumatology . 2003 (4)

[5] Endothelin levels in Henoch-Schonlein purpura [J].

Muslu, A ;

Islek, I ;

Gok, F ;

Aliyazicioglu, Y ;

Dagdemir, A ;

Dundaroz, R ;

Kucukoduk, S ;

Sakarcan, A .

PEDIATRIC NEPHROLOGY, 2002, 17 (11) :922-927

[6]

Complement activation through the lectin pathway in patients with Henoch-Sch?nlein purpura nephritis[J] . Morito Endo,Hiroyuki Ohi,Isao Ohsawa,Takayuki Fujita,Misao Matsushita,Teizo Fujita.American Journal of Kidney Diseases . 2000 (3)

[7]

Haemophilus parainfluenzae Antigen and Antibody in Children With IgA Nephropathy and Henoch-Sch?nlein Nephritis[J] . Yuko Ogura,Satoru Suzuki,Taku Shirakawa,Miwa Masuda,Hajime Nakamura,Kazumoto Iijima,Norishige Yoshikawa.American Journal of Kidney Diseases . 2000 (1)

[8]

Henoch-Schonlein purpura and streptococcal infection: a prospective case-control study[J] . Mahmoud Al-Sheyyab,Anwar Batieha,Hatem El-Shanti,Azhar Daoud.Annals of Tropical Paediatrics . 1999 (3)

[9] The role of cytokines in Henoch Schonlein Purpura [J].

Besbas, N ;

Saatci, U ;

Ruacan, S ;

Ozen, S ;

Sungur, A ;

Bakkaloglu, A ;

ElNahas, AM .

SCANDINAVIAN JOURNAL OF RHEUMATOLOGY, 1997, 26 (06) :456-460

← 1 →