胰高血糖素样肽-1分泌调控机制的研究进展

被引:7
作者
熊周怡
张振
机构
[1] 南方医科大学珠江医院内分泌科
关键词
D O I
10.13820/j.cnki.gdyx.2015.18.053
中图分类号
R587.1 [糖尿病];
学科分类号
100201 [内科学];
摘要
<正>胰高血糖素样肽-1(glucagon-like peptide 1,GLP-1)作为肠道L细胞分泌的主要激素,与糖依赖性胰岛素释放肽(glucose-dependent insulinotropic polypeptide)一起组成肠促胰素发挥"肠促胰素效应",介导高达70%的葡萄糖诱导的胰岛素分泌[1]。多项研究均表明在肥胖和2型糖尿病患者中GLP-1的分泌明显减少[2-3],促进GLP-1分泌、抑制其
引用
收藏
页码:2910 / 2912
页数:3
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