姜黄素治疗泌尿生殖系统癌症的作用机制研究进展

被引：19

作者：

韩伟 ^{[1
]}

雷勇胜 ^{[2
]}

机构：

[1] 天津市静海区医院中药房

[2] 天津药物研究院

来源：

现代药物与临床 | 2016年 / 31卷 / 02期

关键词：

姜黄素; 膀胱癌; 肾癌; 前列腺癌; 宫颈癌; 卵巢癌;

D O I：

暂无

中图分类号：

R273 [中医肿瘤科];

学科分类号：

100502 [中医临床基础];

摘要：

姜黄素是姜黄的主要活性成分,应用于各种疾病领域。研究表明,姜黄素对多个系统相关癌症都具有保护效应。其分子作用机制是通过抑制多个水平细胞的信号传导途径实现的。姜黄素通过与目标分子形成黏合物直接或间接地抑制其细胞的致癌性,这些目标分子包括转录因子、生长因子、酶、激酶、活性细胞激素、浆液、抗性蛋白。主要阐明了姜黄素对泌尿生殖系统癌症的抗癌疗效,以及其分子传导途径,为其在癌症治疗中更广泛的应用提供参考。

引用

页码：260 / 264

页数：5

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