肿瘤坏死因子与脑缺血再灌注损伤

被引:1
作者
高敏
董秀兰
机构
[1] 辽宁医学院附属第一医院神经内科
关键词
肿瘤坏死因子(TNF-α); 脑缺血再灌注;
D O I
暂无
中图分类号
R741 [神经病学];
学科分类号
摘要
肿瘤坏死因子-α(TNF-α)是一种具有广泛生物学功能的细胞因子,参与机体免疫应答和炎症反应。脑缺血再灌注后脑内TNF-α的表达增加,在再灌注损伤病理过程中TNF-α具有损伤与修复双重作用。其作用机制与致炎、促凝血机制、血脑屏障破坏、诱导缺血耐受及神经生长因子生成等有关。
引用
收藏
页码:190 / 191
页数:2
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