乳腺癌术后早期辅助化疗的安全性

AIM To investigate the safety timing of immediately postoperative chemotherapy in the patients with breast cancer. METHODS Thirty two patients with breast cancer of classification Ⅱ were admitted to our hospital, were performed on a breast radical resection. The patients were divided randomly into 2 groups and accepted chemotherapy at day 1 (group 1) and day 8 (group 2) after operation respectively, to observe the effect of healing of surgical wound, a response to chemotherapy and a change of IL 2 and sIL 2R lever in serum. RESULTS There were no significant differences between 2 groups in healing of surgical incisions. A few patients in 2 groups felt nausea and vomit but the symptoms were disappeared when they treated based on the correct diagnosis. Also there were no differences between 2 groups on the fall of the number of white blood cells and a similar tend towards in change of IL 2, sIL 2R lever in serum. CONCLUSION Early postoperative adjuvant chemotherapy with better curative effects and fewer side effects durgs will not effect the ability of surgical wound healing and increase the postoperative complications. The immunity function of the body will not depress. A positive effect occurs both on improvement of the 5 year survival rate and on reducing the recurrent rate in patients with breast cancer.