Let-7在肺癌诊断、治疗及预后评估中的作用

被引：7

作者：

段影

邹跃

江其生

高俊

李晓

李振源

吕进

机构：

[1] 火箭军总医院(锦州医科大学火箭军总医院实习基地)

来源：

现代肿瘤医学 | 2017年 / 25卷 / 02期

关键词：

肺癌; Let-7; 综述; 诊断; 治疗; 预后;

D O I：

暂无

中图分类号：

R734.2 [肺肿瘤];

学科分类号：

100117 [系统生物医学];

摘要：

肺癌是世界范围内发病率与病死率均居首位的恶性肿瘤,目前缺乏理想的早期诊断手段及有效的治疗方法。Let-7异常表达与肺癌的发生发展密切相关。根据大量研究表明,Let-7通过抑制相关癌基因的表达、肿瘤血管生成、提高放化疗和靶向治疗的敏感性,来抑制肺癌的发生和发展。本文就Let-7与肺癌的诊断、治疗、预后评估等方面的研究现状作一综述。

引用

页码：292 / 296

页数：5

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