幽门螺杆菌感染与结直肠息肉发生的关系

被引:24
作者
阮玉凤 [1 ]
万霜 [1 ]
孙璟 [1 ]
江石湖 [2 ]
机构
[1] 上海交通大学医学院附属瑞金医院老年科
[2] 上海交通大学医学院附属瑞金医院消化科
关键词
幽门螺杆菌; 结直肠息肉; 感染;
D O I
暂无
中图分类号
R735.34 [];
学科分类号
摘要
目的探索幽门螺杆菌(Hp)感染与结直肠息肉发生的相关性,同时分析Hp感染与结直肠息肉临床特征的关系。方法从瑞金医院体检人群中选取接受胃肠镜检查者,随机选出120例结直肠息肉检出患者作为病例组,另150例结直肠无明显异常者列为对照,所有入选人群均经13 C呼气试验检查判断有无Hp感染。结果结直肠息肉组Hp阳性率显著高于非息肉组(85%比74%,χ2=4.28,P=0.037),当考虑Hp感染与结直肠息肉临床特征的关系时,发现在直肠、乙状结肠以及降结肠息肉患者中,Hp阳性检出率较Hp阴性组明显增高,差异有统计学意义(P=0.038)。且Hp阳性组与Hp阴性组相比,多发性息肉所占比例较单发高,差异有统计学意义(P=0.004)。结论 Hp感染可增加结直肠息肉的发生风险,其具体致病机制有待进一步研究。
引用
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页码:344 / 347
页数:4
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