NLRP3及其在口腔疾病中的研究进展

被引：5

作者：

宋智

姜澜

林正梅

机构：

[1] 中山大学光华口腔医学院·附属口腔医院,广东省口腔医学重点实验室

来源：

中华口腔医学研究杂志(电子版) | 2012年 / 6卷 / 05期

关键词：

NLRP3; 炎性体; 白细胞介素1β; 天然免疫;

D O I：

暂无

中图分类号：

R780.2 [口腔病理学];

学科分类号：

100302 [口腔临床医学];

摘要：

NLRP3受体是天然免疫系统细胞浆型模式识别受体中核苷酸结合寡聚化结构域样受体(NLR)家族的一个重要成员,在机体固有免疫应答中发挥独特的功能,其特点是可以通过形成复杂的蛋白质复合体——炎性体,介导炎症反应和细胞死亡。NLRP3炎性体在多种疾病和炎症反应中发挥重要作用,下面就NLRP3受体的结构、功能及其在口腔疾病中的作用作一综述。

引用

页码：464 / 467

页数：4

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