In order to observe the therapeutic effect of external therapy of "RUYI JINHUANG SAN" (RJS) and 25 % magnesium sulfate solution (MSS) on radial styloid process tenosynovitis (RSPT), 200 cases of RSPT were divided into two groups: the treated and the control, which were treated for three weeks by the external application of RJS and MSS and by local blockage, respectively; the effective rates of the two groups were observed after the treatment courses. The results showed that the effective rates of the treated and the control were 94 % and 93 %, respectively; the comparison of the two groups showed no significant difference (P > 0.01) through χ2 test, suggesting that RJS and MSS have a strong function to remove the swellings and pains.