下丘脑核转录因子NF-kB的临床研究进展

被引：23

作者：

李凡

常彦青

丁军

机构：

[1] 解放军白求恩国际和平医院干部病房

来源：

解放军医药杂志 | 2016年 / 28卷 / 11期

关键词：

转录因子; NF-kB; 下丘脑; 炎症;

D O I：

暂无

中图分类号：

R363 [病理生理学];

学科分类号：

100103 [病原生物学];

摘要：

<正>核转录因子NF-k B(nuclear factor kappa B,NFk B)是几乎存在于所有细胞的快反应转录因子,其作用为调控大量基因的转录,与其调控的细胞因子参与炎症反应、免疫反应、细胞凋亡等生物进程。在正常生理过程和疾病的发生中有重要作用。近年来,NF-k B在多种衰老性疾病,如肥胖、代谢综合征以及帕金森氏病中的关键性作用机制得到越来越多的关注[1],有希望成为今后的药物作用靶点,现将

引用

收藏

页码：113 / 116

页数：4

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