新疆地区溃疡性结肠炎发病的相关危险因素分析

被引：12

作者：

何玉环 ^{[1
,2
]}

高峰 ^{[1
]}

卢加杰 ^{[1
]}

艾合买江 ^{[1
]}

李月娴 ^{[1
]}

机构：

[1] 新疆维吾尔自治区人民医院消化科

[2] 重庆长寿区人民医院消化科

来源：

实用医学杂志 | 2013年 / 29卷 / 18期

关键词：

溃疡性结肠炎; 问卷调查; 危险因素; 病例对照研究;

D O I：

暂无

中图分类号：

R574.62 [结肠疾病];

学科分类号：

100201 [内科学];

摘要：

目的:探讨溃疡性结肠炎(UC)发病可能的危险因素。方法:经结肠镜检查和病理活检确诊的101例初发型UC患者为病例组,以同期结肠镜检查为正常肠黏膜的非结肠疾病患者101例作为对照组,采用问卷调查的方式采集人口统计学资料、生活方式、饮食习惯等信息,对可能与UC发病相关的11个变量行单因素分析,对差异有统计学意义的变量行多因素Logistic回归分析。结果:单因素分析显示,对于男性患者饮酒、吸烟、油腻饮食、肠道感染、精神紧张、牛奶摄入6个变量与UC发病有关,多因素Logistic回归分析显示偶尔摄入牛奶(P=0.011,OR=4.269,95%CI:1.404～12.976)为男性UC发病的危险因素,吸烟(P=0.003,OR=0.081,95%CI:0.015～0.431)可能是男性UC发病的保护因素;而对于女性患者油腻饮食、精神紧张、牛奶摄入3个变量与UC发病有关,多因素Logistic回归分析显示精神紧张(P=0.012,OR=4.421,95%CI:1.380～14.161)、偶尔摄入牛奶(P=0.006,OR=4.029,95%CI:1.492～10.878)为女性UC发病的危险因素。结论:牛奶摄入、精神紧张可能是UC的致病危险因素,而吸烟可能是UC发病的保护因素。

引用

页码：3070 / 3073

页数：4

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