正常人和垂体-肾上腺疾病患者血清促肾上腺皮质激素原氨基端肽(N-POMC)水平及其临床意义

被引：13

作者：

陆召麟

潘志耆

张洁萍

机构：

[1] 北京协和医院内分泌科

来源：

中华内分泌代谢杂志 | 1985年 / 02期

关键词：

N-POMC; 不均一性; ACTH; 柯兴氏综合征; 血清; 垂体瘤; 正常人; 肾上腺疾病; 内分泌病; 患者;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

本文报告了用RIA法测定正常人和各种垂体-肾上腺疾病患者血清N-POMC水平。结果显示:柯兴氏病患者8Am值明显高于正常人和单纯肥胖者,且失去正常的昼夜节律和不能被地塞米松(小剂量)所抑制;柯兴氏综合征因肾上腺皮质肿瘤者8Am和0Am值均<100pg/ml;Nelson’s综合征和Addi-son’s病者大大高于正常,而肾上腺皮质功能正常的色素沉着者在正常范围。先天性肾上腺皮质增生者有不同程度升高。说明血清N-POMC测定对上述各病的诊断及临床研究有重要意义。本文还初步探讨了血清N-POMC分子的不均一性。

引用

页码：3 / 6+62

页数：5

共 8 条

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