重复经颅磁刺激治疗脑卒中后吞咽障碍的Meta分析

被引：16

作者：

郭桂珍

韩荣胜

王有清

刘庆春

机构：

[1] 青海省第五人民医院神经内科

来源：

武汉大学学报(医学版) | 2018年 / 39卷 / 05期

关键词：

重复经颅磁刺激; 脑卒中后吞咽障碍; 随机对照试验; Meta分析;

D O I：

10.14188/j.1671-8852.2018.0262

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

100204 [神经病学];

摘要：

目的:对重复经颅磁刺激治疗脑卒中后吞咽障碍(PSD)的疗效进行Meta分析。方法:计算机检索PubMed、EMbase、Cochrane library、CNKI、VIP、CBM和万方数据库中关于重复经颅磁刺激改善PSD的随机对照试验(RCT),同时追溯纳入文献的参考文献。检索时限均为从建库至2018年1月。由2名评价员按照纳入与排除标准独立进行文献筛选、资料提取和质量评价后,采用RevMan 5.3软件进行Meta分析。结果:共纳入7个RCT,178例患者(试验组n=93,对照组n=85)。Meta分析结果显示,与对照组相比,rTMS治疗能够改善PSD患者的总体吞咽功能[SMD=-1.00,95%CI(-1.67,-0.33),P=0.004],提高了BI评分[SMD=1.25,95%CI(0.78,1.73),P=0.000 1]。结论:rTMS可在一定程度上改善脑卒中患者的吞咽功能,提高患者的自我生活能力。

引用

页码：855 / 860

页数：6

共 13 条

[1]

Repetitive transcranial magnetic stimulation for rehabilitation of poststroke dysphagia: A randomized, double-blind clinical trial [J].

Du, Juan ;

Yang, Fang ;

Liu, Ling ;

Hu, Jingze ;

Cai, Biyang ;

Liu, Wenhua ;

Xu, Gelin ;

Liu, Xinfeng .

CLINICAL NEUROPHYSIOLOGY, 2016, 127 (03) :1907-1913

[2]

Transcranial non-invasive brain stimulation in swallowing rehabilitation following stroke — A review of the literature.[J].Sebastian H. Doeltgen;Lynley V. Bradnam;Jessica A. Young;Eric Fong.Physiology & Behavior.2015,

[3]

Sequential Evolution of Cortical Activity and Effective Connectivity of Swallowing Using fMRI [J].

Mihai, Paul Glad ;

Otto, Mareile ;

Platz, Thomas ;

Eickhoff, Simon B. ;

Lotze, Martin .

HUMAN BRAIN MAPPING, 2014, 35 (12) :5962-5973

[4]

Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS) [J].

Lefaucheur, Jean-Pascal ;

Andre-Obadia, Nathalie ;

Antal, Andrea ;

Ayache, Samar S. ;

Baeken, Chris ;

Benninger, David H. ;

Cantello, Roberto M. ;

Cincotta, Massimo ;

de Carvalho, Mamede ;

De Ridder, Dirk ;

Devanne, Herve ;

Di Lazzaro, Vincenzo ;

Filipovic, Sasa R. ;

Hummel, Friedhelm C. ;

Jaaskelainen, Satu K. ;

Kimiskidis, Vasilios K. ;

Koch, Giacomo ;

Langguth, Berthold ;

Nyffeler, Thomas ;

Oliviero, Antonio ;

Padberg, Frank ;

Poulet, Emmanuel ;

Rossi, Simone ;

Rossini, Paolo Maria ;

Rothwell, John C. ;

Schonfeldt-Lecuona, Carlos ;

Siebner, Hartwig R. ;

Slotema, Christina W. ;

Stagg, Charlotte J. ;

Valls-Sole, Josep ;

Ziemann, Ulf ;

Paulus, Walter ;

Garcia-Larrea, Luis .

CLINICAL NEUROPHYSIOLOGY, 2014, 125 (11) :2150-2206

[5]

Effect of Low-Frequency rTMS and NMES on Subacute Unilateral Hemispheric Stroke With Dysphagia [J].

Lim, Kil-Byung ;

Lee, Hong-Jae ;

Yoo, Jeehyun ;

Kwon, Yong-Geol .

ANNALS OF REHABILITATION MEDICINE-ARM, 2014, 38 (05) :592-602

[6]

Intake of thickened liquids by hospitalized adults with dysphagia after stroke [J].

Murray, Jo ;

Miller, Michelle ;

Doeltgen, Sebastian ;

Scholten, Ingrid .

INTERNATIONAL JOURNAL OF SPEECH-LANGUAGE PATHOLOGY, 2014, 16 (05) :486-494

[7]

The effect of 5Hz high‐frequency rTMS over contralesional pharyngeal motor cortex in post‐stroke oropharyngeal dysphagia: a randomized controlled study.[J].J.‐W. Park;J.‐C. Oh;J.‐W. Lee;J.‐S. Yeo;K. H. Ryu.Neurogastroenterology & Motility.2012, 4

[8]

Therapeutic role of rTMS on recovery of dysphagia in patients with lateral medullary syndrome and brainstem infarction [J].