心肌缺血/再灌注损伤保护作用机制的研究

被引：9

作者：

潘国焰

林荣

机构：

[1] 福建医科大学附属泉州市第一医院心内科

来源：

医学综述 | 2013年 / 19卷 / 08期

关键词：

缺血/再灌注损伤; 预适应; 后适应; 心肌保护作用机制;

D O I：

暂无

中图分类号：

R542.22 [];

学科分类号：

1002 ; 100201 ;

摘要：

心肌缺血的再灌注治疗一方面恢复了心肌的血供,另一方面可能加重缺血心肌的损伤。心肌缺血/再灌注损伤一直以来是心血管医疗工作者的焦点问题。在保证再灌注治疗的心肌保护作用不受影响的情况下,如何减少再灌注损伤,国内外研究者们历经了艰辛的探索,相继提出了心肌缺血预适应-心肌药物预适应-心肌缺血后适应-心肌药物后适应的概念。该文就当今这一研究新热点及其发生、发展过程和心肌保护作用机制等进行综述。

引用

页码：1368 / 1372

页数：5

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