腰椎间盘退变MRI:T1rho值与Pfirrmann分级及T2值的相关性

被引：19

作者：

刘珍珍 ^{[1
]}

陈建宇 ^{[2
]}

蔡兆熙 ^{[2
]}

蒋新华 ^{[3
]}

张娅 ^{[4
]}

杨泽宏 ^{[2
]}

雷立昌 ^{[2
]}

机构：

[1] 中山大学附属第三医院放射科

[2] 中山大学附属孙逸仙纪念医院放射科

[3] 中山大学肿瘤防治中心影像与微创介入中心

[4] 云南省肿瘤医院放射科

来源：

中国医学影像技术 | 2014年 / 30卷 / 02期

关键词：

腰椎; 椎间盘退变; 磁共振成像;

D O I：

暂无

中图分类号：

R681.53 []; R445.2 [核磁共振成像];

学科分类号：

100231 [临床病理学];

摘要：

目的探讨T1rho值对椎间盘早期退变的预测价值及其与Pfirrmann分级和T2值的相关性。方法对93例腰背痛患者行腰椎MR检查,采集腰椎矢状位T1WI及T2WI、轴位T2WI、矢状位T1rho及T2-mapping。利用矢状位T2WI对腰椎间盘退变进行Pfirrmann分级,矢状位T1rho及T2-mapping上分别测量NP区和AF区T1rho值及T2值,分析椎间盘T1rho值与Pfirrmann分级及T2值的关系。结果 93例中,PfirrmannⅠⅤ级腰椎间盘数分别为0、235、179、41、10个。除PfirrmannⅤ级外,其余各级NP区T1rho值均高于AF区（P<0.001）;随椎间盘退变程度加重,NP区T1rho值降低（PfirrmannⅣ级和Ⅴ级间除外）,PfirrmannⅡ级AF区T1rho值均高于PfirrmannⅢⅤ级;NP区及AF区T1rho值与退变分级均呈负相关（NP区:r=-0.75,P<0.001;AF区:r=-0.32,P<0.001）;PfirrmannⅡⅢ级腰椎间盘NP区T1rho值与T2值呈中度相关（PfirrmannⅡ级:r=0.46;PfirrmannⅢ级:r=0.44;PfirrmannⅣ级:r=0.16;PfirrmannⅤ级:r=0.04）;AF区T1rho值与T2值相关性差（PfirrmannⅡ级:r=0.13;PfirrmannⅢ级:r=0.15;PfirrmannⅣ级:r=0.19;PfirrmannⅤ级:r=0.62）。结论 T1rho对腰椎间盘早期退变具有预测价值,NP区表现明显;椎间盘早期退变过程中,NP区T1rho值与T2值呈中度相关。

引用

收藏

页码：260 / 264

页数：5

相关论文

共 12 条

[1]

Noninvasive quantification of human nucleus pulposus pressure with use of T1rho-weighted magnetic resonance imaging..Nguyen An M;Johannessen Wade;Yoder Jonathon H;Wheaton Andrew J;Vresilovic Edward J;Borthakur Arijitt;Elliott Dawn M;.The Journal of bone and joint surgery. American volume.2008, 04

[2]

Assessment of glycosaminoglycan content in intervertebral discs using chemical exchange saturation transfer at 3.0 Tesla: preliminary results in patients with low-back pain [J].

Haneder, Stefan ;

Apprich, Sebastian R. ;

Schmitt, Benjamin ;

Michaely, Henrik J. ;

Schoenberg, Stefan O. ;

Friedrich, Klaus M. ;

Trattnig, Siegfried .

EUROPEAN RADIOLOGY, 2013, 23 (03) :861-868

[3]

T1rho and T2 relaxation times for lumbar disc degeneration: an in vivo comparative study at 3.0-Tesla MRI.[J].Yi-Xiang J. Wang;Feng Zhao;James F. Griffith;Greta S. P. Mok;Jason C. S. Leung;Anil T. Ahuja;Jing Yuan.European Radiology.2012, 1

[4]

T1ρ Magnetic Resonance Imaging Quantification of Early Lumbar Intervertebral Disc Degeneration in Healthy Young Adults [J].

Zobel, Bruno Beomonte ;

Vadala, Gianluca ;

Del Vescovo, Riccardo ;

Battisti, Sofia ;

Martina, Francesca Maria ;

Stellato, Luigi ;

Leoncini, Emanuele ;

Borthakur, Arijitt ;

Denaro, Vincenzo .

SPINE, 2012, 37 (14) :1224-1230

[5]

Assessment of glycosaminoglycan concentration changes in the intervertebral disc via chemical exchange saturation transfer [J].

Saar, Galit ;

Zhang, Boyang ;

Ling, Wen ;

Regatte, Ravinder R. ;

Navon, Gil ;

Jerschow, Alexej .

NMR IN BIOMEDICINE, 2012, 25 (02) :255-261

[6]

T1ρ Magnetic Resonance Imaging and Discography Pressure as Novel Biomarkers for Disc Degeneration and Low Back Pain [J].

Borthakur, Arijitt ;

Maurer, Philip M. ;

Fenty, Matthew ;

Wang, Chenyang ;

Berger, Rachelle ;

Yoder, Jonathon ;

Balderston, Richard A. ;

Elliott, Dawn M. .

SPINE, 2011, 36 (25) :2190-2196

[7]

Lumbar intervertebral disc abnormalities: comparison of quantitative T2 mapping with conventional MR at 3.0 T [J].

Trattnig, Siegfried ;

Stelzeneder, David ;

Goed, Sabine ;

Reissegger, Michael ;

Mamisch, Tallal C. ;

Paternostro-Sluga, Tatjana ;

Weber, Michael ;

Szomolanyi, Pavol ;

Welsch, Goetz H. .

EUROPEAN RADIOLOGY, 2010, 20 (11) :2715-2722

[8]

In vivo 3.0‐tesla magnetic resonance T<sub>1ρ</sub> and T<sub>2</sub> relaxation mapping in subjects with intervertebral disc degeneration and clinical symptoms.[J].GabrielleBlumenkrantz;JinZuo;XiaojuanLi;JohnKornak;Thomas M.Link;SharmilaMajumdar.Magn. Reson. Med..2010, 5

[9]

Prevalence of Degenerative Imaging Findings in Lumbar Magnetic Resonance Imaging Among Young Adults [J].

Takatalo, Jani ;

Karppinen, Jaro ;

Niinimaki, Jaakko ;

Taimela, Simo ;

Nayha, Simo ;

Jarvelin, Marjo-Riitta ;

Kyllonen, Eero ;

Tervonen, Osmo .

SPINE, 2009, 34 (16) :1716-1721

[10]

A feasibility study of in vivo T 1ρ imaging of the intervertebral disc.[J].Gabrielle Blumenkrantz;Xiaojuan Li;Eric T. Han;David C. Newitt;Jason C. Crane;Thomas M. Link;Sharmila Majumdar.Magnetic Resonance Imaging.2006, 8