促性腺激素释放激素拮抗剂在性早熟治疗中的研究进展

被引:1
作者
孙青
李海浪
机构
[1] 东南大学医学院儿科
关键词
促性腺素释放激素; 青春期,早熟;
D O I
暂无
中图分类号
R725.8 [小儿内分泌腺疾病及代谢病];
学科分类号
100202 ;
摘要
促性腺激素释放激素(GnRH)激动剂是目前治疗真性性早熟的首选药物。但是在使用初期会引起促性腺激素一过性升高(即flare-up效应),该效应不利于性早熟的治疗。动物实验和临床研究结果表明,GnRH拮抗剂对性激素有很强的抑制作用,并且无flare-up效应,因此成为更理想的替代GnRH激动剂治疗性早熟的药物。
引用
收藏
页码:123 / 125
页数:3
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