动脉粥样硬化生物标志物在冠心病中的应用价值

被引:16
作者
罗甜甜
田迪
刘挺榕
孙海阁
郭志刚
机构
[1] 南方医科大学南方医院心内科
基金
广东省自然科学基金; 广东省科技计划;
关键词
D O I
10.13820/j.cnki.gdyx.2014.01.063
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
100201 [内科学];
摘要
<正>动脉粥样硬化(AS)是以血脂代谢异常、血小板聚集和血栓形成为基础的血管慢性炎症性疾病,可引发心肌梗死、脑梗死等严重危害人类健康和生命的疾病。大量基础实验和临床研究发现,脂质代谢异常,低密度脂蛋白(LDL)含量的增加,尤其是氧化低密度脂蛋白(Ox-LDL)的增加,高度提示AS的发生;炎症反应增加,一些炎症因子的升高,如C反应蛋白(CRP)、白细胞介素6(IL-6)、可溶性细胞间黏附分子-1(sICAM-1)等因子的升高,也与AS的发生、进展有
引用
收藏
页码:144 / 147
页数:4
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