CT灌注原始图像不匹配模型评价急性缺血性脑卒中缺血半暗带和梗死核心的价值

被引：3

作者：

王效春

高培毅

薛静

刘光锐

马丽

王晨

机构：

[1] 首都医科大学附属北京天坛医院神经影像中心北京市神经外科研究所

来源：

中华放射学杂志 | 2009年 / 03期

关键词：

脑血管意外; 体层摄影术,X线计算机; 灌流;

D O I：

暂无

中图分类号：

R686 [筋腱、韧带、滑囊疾病及损伤];

学科分类号：

摘要：

目的评价CT灌注原始图像(CT peffusion source images,CTP-SI)不匹配模型在判断缺血半暗带和梗死核心中的价值。方法 24例急性缺血性脑卒中患者(发病时间<9 h)行"一站式急性缺血性脑卒中CT"扫描,分析基线动脉期及静脉期CTP-SI Alberta卒中早期CT评分(Alberta Stroke Program Early CT Score,ASPECTS),并与随访影像ASPECTS进行对照。采用Wilcoxon秩和检验比较动脉期与静脉期CTP-SI ASPECTS之问的统计学差异;应用多元线性回归分析基线动脉期、静脉期CTP-SI与随访影像ASPECTS之间的线性依存关系。结果基线动脉期、静脉期和随访影像的CTP-SI ASPECTS中位数分别为9.0分(2.0～10.0分)、9.3分(6.5～10.0分)、9.0分(7.0～10.0分)。动脉期与静脉期CTP-SI ASPECTS差异有统计学意义(X=-2.812,P=0.005),10例静脉期CTP-SI ASPECTS大于动脉期,14例静脉期CTP-SI ASPECTS等于动脉期;静脉期CTP-SIASPECTS与随访影像ASPECTS之间的线性依存关系有统计学意义,标准化回归系数(Beta)=0.715,P=0.003。结论 CT灌注原始图像不匹配模型可以预测缺血半暗带和梗死核心,为临床医师制定治疗方案时提供了更多的选择。

引用

共 7 条

[1]

Magnetic resonance imaging and computed tomography in emergency assessment of patients with suspected acute stroke: a prospective comparison[J] . Julio A Chalela,Chelsea S Kidwell,Lauren M Nentwich,Marie Luby,John A Butman,Andrew M Demchuk,Michael D Hill,Nicholas Patronas,Lawrence Latour,Steven Warach.The Lancet . 2007 (9558)

[2] Comparison of CT perfusion and angiography and MRI in selecting stroke patients for acute treatment [J].

Wintermark, M. ;

Meuli, R. ;

Browaeys, P. ;

Reichhart, M. ;

Bogousslavsky, J. ;

Schnyder, P. ;

Michel, P. .

NEUROLOGY, 2007, 68 (09) :694-697

[3]

Perfusion-CT Assessment of Infarct Core and Penumbra: Receiver Operating Characteristic Curve Analysis in 130 Patients Suspected of Acute Hemispheric Stroke[J] . Max Wintermark,Adam E. Flanders,Birgitta Velthuis,Reto Meuli,Maarten van Leeuwen,Dorit Goldsher,Carissa Pineda,Joaquin Serena,Irene van der Schaaf,Annet Waaijer,James Anderson,Gary Nesbit,Igal Gabriely,Victoria Medina,Ana Quiles,Scott Pohlman,Marcel Quist,Pierre Schnyder,Julien Bogousslavsky,William P. Dillon,Salvador Pedraza.Stroke . 2

[4]

Perfusion computed tomography: Prediction of final infarct extent and stroke outcome[J] . Mark W.Parsons,Elizabeth M.Pepper,VirgilChan,SabbirSiddique,SivaRajaratnam,Grant A.Bateman,Christopher R.Levi.Ann Neurol. . 2005 (5)

[5]

ASPECTS on CTA Source Images Versus Unenhanced CT: Added Value in Predicting Final Infarct Extent and Clinical Outcome[J] . Shelagh B. Coutts,Michael H. Lev,Michael Eliasziw,Luca Roccatagliata,Michael D. Hill,Lee H. Schwamm,J.H. Warwick Pexman,Walter J. Koroshetz,Mark E. Hudon,Alastair M. Buchan,R. Gilberto Gonzalez,Andrew M. Demchuk.Stroke . 2004 (11)

[6]

Effect of Intravenous Thrombolysis on MRI Parameters and Functional Outcome in Acute Stroke ＜6 Hours[J] . Stroke: Journal of the American Heart Association . 2002 (10)

[7] Examining the lacunar hypothesis with diffusion and perfusion magnetic resonance Imaging [J].

Gerraty, RP ;

Parsons, MW ;

Barber, PA ;

Darby, DG ;

Desmond, PM ;

Tress, BM ;

Davis, SM .

STROKE, 2002, 33 (08) :2019-2024

← 1 →