CT灌注原始图像不匹配模型评价急性缺血性脑卒中缺血半暗带和梗死核心的价值

被引:3
作者
王效春
高培毅
薛静
刘光锐
马丽
王晨
机构
[1] 首都医科大学附属北京天坛医院神经影像中心北京市神经外科研究所
关键词
脑血管意外; 体层摄影术,X线计算机; 灌流;
D O I
暂无
中图分类号
R686 [筋腱、韧带、滑囊疾病及损伤];
学科分类号
摘要
目的评价CT灌注原始图像(CT peffusion source images,CTP-SI)不匹配模型在判断缺血半暗带和梗死核心中的价值。方法 24例急性缺血性脑卒中患者(发病时间<9 h)行"一站式急性缺血性脑卒中CT"扫描,分析基线动脉期及静脉期CTP-SI Alberta卒中早期CT评分(Alberta Stroke Program Early CT Score,ASPECTS),并与随访影像ASPECTS进行对照。采用Wilcoxon秩和检验比较动脉期与静脉期CTP-SI ASPECTS之问的统计学差异;应用多元线性回归分析基线动脉期、静脉期CTP-SI与随访影像ASPECTS之间的线性依存关系。结果基线动脉期、静脉期和随访影像的CTP-SI ASPECTS中位数分别为9.0分(2.0~10.0分)、9.3分(6.5~10.0分)、9.0分(7.0~10.0分)。动脉期与静脉期CTP-SI ASPECTS差异有统计学意义(X=-2.812,P=0.005),10例静脉期CTP-SI ASPECTS大于动脉期,14例静脉期CTP-SI ASPECTS等于动脉期;静脉期CTP-SIASPECTS与随访影像ASPECTS之间的线性依存关系有统计学意义,标准化回归系数(Beta)=0.715,P=0.003。结论 CT灌注原始图像不匹配模型可以预测缺血半暗带和梗死核心,为临床医师制定治疗方案时提供了更多的选择。
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