小剂量阿斯匹林预防妊高征疗效研究

被引:1
作者
吴静
杨伟文
沈文红
何扬
机构
[1] 苏州医学院附属第一医院妇产科
[2] 苏州医学院血栓研究室
关键词
阿斯匹林; 妊高征; 前列腺素类;
D O I
暂无
中图分类号
R714.246 [];
学科分类号
100211 ;
摘要
采用前瞻性随机临床研究有妊高征高危因素孕20~38W 孕妇104名,随机分为2组。服药组在孕30W 后予阿斯匹林50mg/d,连服3~5周。结果:妊高征孕妇血浆 TXB2及 TXB2/6—Ke-toPGF1α明显高于未发生妊高征者(P<0.01)。服药组妊高征显著低于对照组(P<0.01),血浆 TXB2及 TXB2/6—KetoPGF1α明显下降(P<0.05)。说明:血浆 TXB2及 TXB2/6—KetoPGF1α升高者妊高征发病率明显增加;阿斯匹林能降低血浆 TXB2浓度和调整 TXB2/6—KetoPGF1α值,可预防妊高征发生。
引用
收藏
页码:551 / 553
页数:3
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