5-脂氧酶与脑缺血炎症反应的关系

被引:2
作者
陈文健
张丽慧
机构
[1] 杭州师范大学基础医学部药理学教研室
基金
浙江省自然科学基金;
关键词
5-脂氧酶; 脑缺血; 炎症; 半胱氨酰白三烯; 受体;
D O I
10.19890/j.cnki.issn1674-6449.2009.06.018
中图分类号
R741 [神经病学];
学科分类号
摘要
炎症反应在脑缺血损伤中发挥重要作用。5-脂氧酶是代谢花生四烯酸产生炎症介质白三烯类的关键酶,其产物中半胱氨酰白三烯可诱导强烈的外周及中枢炎症性病变。因此,深入了解5-脂氧酶与脑缺血后炎症损伤的关系,对脑缺血损伤机制及新型抗脑缺血药物研究均有积极意义。
引用
收藏
页码:471 / 473
页数:3
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