原发性肝细胞癌合并胆管癌栓的外科诊治分析

被引:6
作者
孙自强 [1 ]
赵文华 [2 ]
张波 [3 ]
于文胜 [3 ]
石学涛 [3 ]
李胜 [3 ]
机构
[1] 山东省济宁医学院附属医院肝胆血管外科
[2] 山东省千佛山医院肿瘤科
[3] 山东省肿瘤防治研究院肝胆外科
关键词
肝肿瘤; 胆管; 肝切除; 肿瘤循环细胞;
D O I
10.16260/j.cnki.1009-2188.2010.04.029
中图分类号
R735.7 [肝肿瘤];
学科分类号
100214 ;
摘要
目的探讨原发性肝细胞癌合并胆管癌栓的诊断及外科治疗效果。方法回顾性总结和分析20例原发性肝细胞癌合并胆管癌栓的外科诊治情况。采用肝叶切除及癌栓取出术7例、单纯胆管癌栓取出3例;肝动脉化疗栓塞术(transcatheter hepatic arterial chemoembolization,TACE)后肝切除加癌栓取出术10例。术后均行胆管引流及TACE。结果术前行TACE的10例患者,术中胆道出血(45.2±12.5)ml,明显少于未行TACE者(90.5±10.5)ml,差异显著(P<0.05)。全部病例均获随访,平均时间22(2~54)个月。肝叶切除及癌栓取出7例,平均生存(21.5±2.8)个月;术前TACE、2周后行肝叶切除加癌栓取出10例,平均生存(28.5±3.1)个月;单纯癌栓取出3例,平均生存(4.1±0.5)个月,术前行TACE组生存时间明显长于其余两组(P<0.05)。结论对原发性肝细胞癌合并胆管癌栓早期诊断、积极切除肿瘤并清除胆管癌栓,配合术前术后TACE术,是改善预后的有效治疗方法。
引用
收藏
页码:251 / 253
页数:3
相关论文
共 8 条
[1]  
Surgical treatment of hepatocellular carcinoma with bile duct tumor thrombi[J]. Bao-Gang Peng, Li-Jian Liang, Shao-Qiang Li, Fan Zhou, Yun-Peng Hua, Shi-Min Luo, Department of Hepatobiliary Surgery, the First Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510080, Guangdong Province, China.World Journal of Gastroenterology. 2005(25)
[2]   原发性肝癌伴胆管癌栓的外科治疗 [J].
彭淑牖 ;
王建伟 ;
刘颖斌 ;
蔡秀军 ;
牟一平 ;
吴育连 ;
方河清 ;
彭承宏 .
中华外科杂志, 2003, (03) :12-14
[3]   Hepatic resection for hepatocellular carcinoma with obstructive jaundice due to biliary tumor thrombi [J].
Yeh, CN ;
Jan, YY ;
Lee, WC ;
Chen, MF .
WORLD JOURNAL OF SURGERY, 2004, 28 (05) :471-474
[4]   Biliary obstruction caused by intrabiliary transplantation from hepatocellular carcinoma [J].
Narita, R ;
Oto, T ;
Mimura, Y ;
Ono, M ;
Abe, S ;
Tabaru, A ;
Yoshikawa, I ;
Tanimoto, A ;
Otsuki, M .
JOURNAL OF GASTROENTEROLOGY, 2002, 37 (01) :55-58
[5]  
Intraductal ultrasonography for hepatocellular carcinoma with tumor thrombi in the bile duct: Comparison with polypoid cholangiocarcinoma[J] . KiichiTamada,NorioIsoda,ShinichiWada,TakeshiTomiyama,AkiraOhashi,YukihiroSatoh,KenichiIdo,KentaroSugano.Journal of Gastroenterology and Hepatology . 2001 (7)
[6]   Combined hepatocellular carcinoma and cholangiocarcinoma growing into the common bile duct [J].
Saito, M ;
Hige, S ;
Takeda, H ;
Tomaru, U ;
Shibata, M ;
Asaka, M .
JOURNAL OF GASTROENTEROLOGY, 2001, 36 (12) :842-847
[7]  
Obstructive jaundice caused by hepatocellular carcinoma: Detection by endoscopic sonography[J] . Yi‐ChiaLee,Hsiu‐PoWang,Shih‐PeiHuang,Yu‐TingChang,Chen‐TuWu,Chang‐ShyueYang,Ming‐ShiangWu,Jaw‐TownLin.J. Clin. Ultrasound . 2001 (6)
[8]   Clinicopathologic evaluation of hepatocellular carcinoma with bile duct thrombi [J].
Satoh, S ;
Ikai, I ;
Honda, G ;
Okabe, H ;
Takeyama, O ;
Yamamoto, Y ;
Yamamoto, N ;
Iimuro, Y ;
Shimahara, Y ;
Yamaoka, Y .
SURGERY, 2000, 128 (05) :779-783