高温及联合60Co—γ射线对L5178y细胞DNA链断裂与修复的影响

被引：1

作者：

黄汉贤

苏燎原

孙国器

机构：

[1] 苏州医学院放射损伤基础教研室,苏州医学院放射损伤基础教研室,苏州医学院放射损伤基础教研室

来源：

癌症 | 1989年 / 01期

关键词：

γ射线; γ辐射; 电磁波; 细胞; DNA; L5178y;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

本实验应用灵敏度较高的同位素标记—硷洗脱法研究了高温及联合60Co—γ射线对L5178y细胞DNA链断裂与修复的影响。结果表明,43℃加温30分钟能明显导致DNA链断裂,并能显著地加强γ射线引起细胞DNA断裂的效应及抑制其修复;42℃则未观察到这些作用。提示高温对DNA结构的损伤及其辐射增敏作用可能存在临界温度。加温顺序对这种辐射增敏作用有影响,照前加温效果较好。

引用

页码：5 / 8

页数：4

共 7 条

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