固醇调节元件结合蛋白1c的研究进展

[1] ADD1 SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose. Foretz M,Pacot C,Dugail I,et al. Molecular and Cellular Biology . 1999

[2] Increased levels of nuclear SREBP-1c associated with fatty liver in two mouse models of diabetes mellitus. Shomomura I,Bashmakov Y,Horton G D,et al. Journal of Biological Chemistry . 1999

[3] Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice. Becard D,Hainault I,Azzout-Marniche D,et al. Diabetes . 2001

[4] Absence of sterol regulatory element-binding protein-1(SREBP-1) ameliorates fatty livers, but not obesity or insulin resistance in lepoblepob mice. Yahagi N,Shimano H,Hasty A H,et al. Journal of Biological Chemistry . 2002

[5] Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes. Shimomura I,Bashmakov Y,Ikemoto S,et al. Proceedings of the National Academy of Sciences of the United States of America . 1999

[6] Leptin-specific patterns of gene expression in white adipose tissue. Soukas A,Cohen P,Socci N D,et al. Genes and Development . 2000

[7] Differential expression of exons 1a and 1c in mRNA for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. Shimomura I,Shimano H,Horton J D,et al. The Journal of Clinical Investigation . 1997

[8] Lipotoxicity ofβ-cells in obesity and in other causes of fatty acid spillover. Unger R H,Zhou Y T. Diabetes .

[9] SREBP-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis related genes. Foretz M,Guichard P,Ferre P,et al. Proceedings of the National Academy of Sciences of the United States of America . 1999

[10] Increased expression of the sterol regulatory element binding protein binding protein(SREBP)-1c gene in insulin receptor substrate-2 (- -)mouse liver. Tobe K,Suzuki R,Aoyama M,et al. Journal of Biological Chemistry . 2001

[1] ADD1 SREBP-1c is required in the activation of hepatic lipogenic gene expression by glucose. Foretz M,Pacot C,Dugail I,et al. Molecular and Cellular Biology . 1999

[2] Increased levels of nuclear SREBP-1c associated with fatty liver in two mouse models of diabetes mellitus. Shomomura I,Bashmakov Y,Horton G D,et al. Journal of Biological Chemistry . 1999

[3] Adenovirus-mediated overexpression of sterol regulatory element binding protein-1c mimics insulin effects on hepatic gene expression and glucose homeostasis in diabetic mice. Becard D,Hainault I,Azzout-Marniche D,et al. Diabetes . 2001

[4] Absence of sterol regulatory element-binding protein-1(SREBP-1) ameliorates fatty livers, but not obesity or insulin resistance in lepoblepob mice. Yahagi N,Shimano H,Hasty A H,et al. Journal of Biological Chemistry . 2002

[5] Insulin selectively increases SREBP-1c mRNA in the livers of rats with streptozotocin-induced diabetes. Shimomura I,Bashmakov Y,Ikemoto S,et al. Proceedings of the National Academy of Sciences of the United States of America . 1999

[6] Leptin-specific patterns of gene expression in white adipose tissue. Soukas A,Cohen P,Socci N D,et al. Genes and Development . 2000

[7] Differential expression of exons 1a and 1c in mRNA for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells. Shimomura I,Shimano H,Horton J D,et al. The Journal of Clinical Investigation . 1997

[8] Lipotoxicity ofβ-cells in obesity and in other causes of fatty acid spillover. Unger R H,Zhou Y T. Diabetes .

[9] SREBP-1c is a major mediator of insulin action on the hepatic expression of glucokinase and lipogenesis related genes. Foretz M,Guichard P,Ferre P,et al. Proceedings of the National Academy of Sciences of the United States of America . 1999

[10] Increased expression of the sterol regulatory element binding protein binding protein(SREBP)-1c gene in insulin receptor substrate-2 (- -)mouse liver. Tobe K,Suzuki R,Aoyama M,et al. Journal of Biological Chemistry . 2001