情感障碍脑磁共振质子波谱研究现状

被引:4
作者
申变红
李国海
机构
[1] 江苏省镇江市第四人民医院
关键词
情感障碍; 抑郁症; H1-MRS;
D O I
10.13479/j.cnki.jip.2009.03.009
中图分类号
R749.4 [情感性精神病];
学科分类号
100205 ;
摘要
磁共振氢质子波谱(H1-MRS)能够检测活体组织生化物的相对含量,是研究脑内神经生化的一种新技术。本文就近年来H1-MRS在情感障碍(抑郁症)各个脑区的研究发现作一综述。
引用
收藏
页码:154 / 157
页数:4
相关论文
共 11 条
[2]  
神经生物学纲要.[M].徐科主编;.科学出版社.2000,
[3]   Reduction in occipital cortex γ-aminobutyric acid concentrations in medication-free recovered unipolar depressed and bipolar subjects [J].
Bhagwagar, Zubin ;
Wylezinska, Marzena ;
Jezzard, Peter ;
Evans, John ;
Ashworth, Fiona ;
Sule, Akeem ;
Matthews, Paul M. ;
Cowen, Philip J. .
BIOLOGICAL PSYCHIATRY, 2007, 61 (06) :806-812
[4]   Normal prefrontal gamma-aminobutyric acid levels in remitted depressed subjects determined by proton magnetic resonance spectroscopy [J].
Hasler, G ;
Neumeister, A ;
van der Veen, JW ;
Tumonis, T ;
Bain, EE ;
Shen, J ;
Drevets, WC ;
Charney, DS .
BIOLOGICAL PSYCHIATRY, 2005, 58 (12) :969-973
[5]   Proton spectroscopy study of the left dorsolateral prefrontal cortex in pediatric depressed patients [J].
Caetano, SC ;
Fonseca, M ;
Olvera, RL ;
Nicoletti, M ;
Hatch, JP ;
Stanley, JA ;
Hunter, K ;
Lafer, B ;
Pliszka, SR ;
Soares, JC .
NEUROSCIENCE LETTERS, 2005, 384 (03) :321-326
[6]   Hippocampal neurochemical pathology in patients at first episode of affective psychosis: a proton magnetic resonance spectroscopic imaging study [J].
Blasi, G ;
Bertolino, A ;
Brudaglio, F ;
Sciota, D ;
Altamura, M ;
Antonucci, N ;
Scarabino, T ;
Weinberger, DR ;
Nardini, M .
PSYCHIATRY RESEARCH-NEUROIMAGING, 2004, 131 (02) :95-105
[7]   Effective electroconvulsive therapy reverses glutamate/glutamine deficit in the left anterior cingulum of unipolar depressed patients [J].
Pfleiderer, B ;
Michael, N ;
Erfurth, A ;
Ohrmann, P ;
Hohmann, U ;
Wolgast, M ;
Fiebich, M ;
Arolt, V ;
Heindel, W .
PSYCHIATRY RESEARCH-NEUROIMAGING, 2003, 122 (03) :185-192
[8]   Focal and lateralized subcortical abnormalities in unipolar major depressive disorder: An automated multivoxel proton magnetic resonance spectroscopy study [J].
Vythilingam, M ;
Charles, HC ;
Tupler, LA ;
Blitchington, T ;
Kelly, L ;
Krishnan, KRR .
BIOLOGICAL PSYCHIATRY, 2003, 54 (07) :744-750
[9]   Neuronal pathology in the hippocampal area of patients with bipolar disorder: A study with proton magnetic resonance spectroscopic imaging [J].
Bertolino, A ;
Frye, M ;
Callicott, JH ;
Mattay, VS ;
Rakow, R ;
Shelton-Repella, J ;
Post, R ;
Weinberger, DR .
BIOLOGICAL PSYCHIATRY, 2003, 53 (10) :906-913
[10]   Decreased N-acetylaspartate in children with familial bipolar disorder [J].
Chang, K ;
Adleman, N ;
Dienes, K ;
Barnea-Goraly, N ;
Reiss, A ;
Ketter, T .
BIOLOGICAL PSYCHIATRY, 2003, 53 (11) :1059-1065