肝细胞性肝癌血清中MIFIL-17IL-10的检测及其临床意义

被引:11
作者
于晓辉 [1 ]
段惠春 [2 ]
杨晓萍 [3 ]
赵夏平 [1 ]
王维 [1 ]
戴飞 [1 ]
机构
[1] 兰州军区兰州总医院消化科
[2] 兰州市石化总院消化科
[3] 兰州军区兰州总医院影像诊断科
关键词
巨噬细胞移动抑制因子; 白细胞介素-17; 白细胞介素-10; 肝细胞性肝癌;
D O I
暂无
中图分类号
R735.7 [肝肿瘤];
学科分类号
100112 [医学生物化学与分子生物学];
摘要
目的:检测肝细胞性肝癌(hepatoceIIuIar carcinoma,HCC)患者外周血中MIF、IL-17、IL-10的含量,并探讨其临床意义。方法:选择48例HCC和36例肝硬化(LC)为实验组,24例健康体检者为对照组。采用酶联免疫吸附(ELISA)法测定实验组和对照组血清中MIF、IL-17及IL-10的含量。结果:HCC组和LC组MIF和IL-17的含量均高于正常对照组,IL-10均低于对照组,差异有统计学意义(P均<0.05);HCC组和LC组MIF、IL-17和IL-10含量差异无统计学意义(P>0.05)。结论:MIF、IL-17及IL-10的紊乱可能与HCC及LC密切相关,具有重要的临床意义。
引用
收藏
页码:714 / 716
页数:3
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