挤出-滚圆法制备微丸的研究进展

被引：66

作者：

刘耀

刘松青

机构：

[1] 第三军医大学附属西南医院药学部

来源：

中国药学杂志 | 2008年 / 06期

关键词：

微丸; 挤出-滚圆法; 影响因素; 药物释放;

D O I：

暂无

中图分类号：

R944 [剂型];

学科分类号：

100702 [药剂学];

摘要：

目的综述挤出-滚圆法的不同因素对于微丸的形成及其释药行为的影响。方法查阅国内外相关文献,进行整理、归纳和总结,以微丸的性质和药物的释放为指标,考察影响挤出-滚圆法的各因素。结果与结论制剂的处方及工艺对微丸均有影响,通过对挤出滚圆中处方和参数的优化,可获得满意的成丸效果及释药行为,以达到制剂目的。

引用

页码：401 / 405

页数：5

共 10 条

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