降钙素原对脓毒症鉴别诊断及预后监测的方法评价

被引:32
作者
张天卿 [1 ]
沈淑男 [2 ]
胡哲清 [1 ]
机构
[1] 宁波, 慈溪市人民医院ICU科
[2] 宁波, 慈溪市人民医院学生办公室
关键词
降钙素; 脓毒症; 预后;
D O I
暂无
中图分类号
R459.7 [急症、急救处理];
学科分类号
100218 ;
摘要
目的评价血清降钙素原(PCT)在脓毒症鉴别诊断及预后监测的价值。方法 76例脓毒症患者, 其中早期脓毒症43例, 严重脓毒症患者20例, 脓毒症休克患者13例。采用免疫荧光法检测血清中PCT和CRP水平。结果脓毒症休克组与严重脓毒症组相比、严重脓毒症组和早期脓毒症组相比, PCT、CRP、APACHE II评分之间均有统计学意义(P<O.05);脓毒症患者血清PCT与APACHEⅡ评分之间存在显著正相关(r=0.57, P<0.05);在使用抗生素治疗后血清PCT可快速下降, 出院前恢复到正常水平, 而CRP在细菌感染被控制后仍维持在高水平, 出院前浓度仍高于正常水平, 其回落速度慢于血清PCT。结论对于鉴别不同程度的脓毒症, PCT是一个很好的血清指标, 还可进行脓毒症预后的监测。
引用
收藏
页码:87 / 89
页数:3
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