痛风发病机制及药物治疗研究现状及展望

被引:49
作者
青玉凤 [1 ,2 ]
周京国 [2 ]
机构
[1] 成都中医药大学风湿免疫科
[2] 川北医学院附属医院风湿血液科
关键词
D O I
暂无
中图分类号
R589.7 [嘌呤(Purine)代谢障碍];
学科分类号
100201 [内科学];
摘要
<正>痛风是嘌呤代谢紊乱和(或)尿酸排泄减少而致血尿酸水平升高,尿酸盐(monosodi umurate,MSU)晶体沉积于组织或器官并引起组织损伤的一组临床综合征,主要表现为反复发作性关节红、肿、热、痛与功能障碍,甚至关节畸形、肾石病及尿酸性肾
引用
收藏
页码:2719 / 2723
页数:5
相关论文
共 12 条
[1]
中药治疗痛风临床疗效Meta分析 [J].
袁红宇 ;
何苗 ;
欧宁 .
中华中医药学刊 , 2011, (03) :666-670
[2]
Treatment of 60 Cases of Gouty Arthritis with Modified Simiao Tang [J].
邱仁斌 ;
沈瑞子 ;
林德就 ;
陈远林 ;
叶红萍 ;
朱函亭 .
Journal of Traditional Chinese Medicine, 2008, (02) :94-97
[3]
加味四妙汤对微晶型尿酸钠致兔急性痛风性关节炎的防治作用 [J].
陈光亮 ;
韩茹 ;
谷仿丽 ;
曹康 ;
李莉 ;
王元勋 .
中国实验方剂学杂志, 2008, (02) :42-45
[4]
Using Allopurinol Above the Dose Based on Creatinine Clearance Is Effective and Safe in Patients With Chronic Gout, Including Those With Renal Impairment [J].
Stamp, Lisa K. ;
O'Donnell, John L. ;
Zhang, Mei ;
James, Jill ;
Frampton, Christopher ;
Barclay, Murray L. ;
Chapman, Peter T. .
ARTHRITIS AND RHEUMATISM, 2011, 63 (02) :412-421
[5]
Simiao pill ameliorates urate underexcretion and renal dysfunction in hyperuricemic mice [J].
Hu, Qing-Hua ;
Jiao, Rui-Qing ;
Wang, Xing ;
Lv, Yao-Zhong ;
Kong, Ling-Dong .
JOURNAL OF ETHNOPHARMACOLOGY, 2010, 128 (03) :685-692
[6]
Gout [J].
Richette, Pascal ;
Bardin, Thomas .
LANCET, 2010, 375 (9711) :318-328
[7]
Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study [J].
Dehghan, Abbas ;
Kottgen, Anna ;
Yang, Qiong ;
Hwang, Shih Jen ;
Kao, W. H. Linda ;
Rivadeneira, Fernando ;
Boerwinkle, Eric ;
Levy, Daniel ;
Hofman, Albert ;
Astor, Brad C. ;
Benjamin, Emelia J. ;
van Duijn, Cornelia M. ;
Witteman, Jacqueline C. ;
Coresh, Josef ;
Fox, Caroline S. .
LANCET, 2008, 372 (9654) :1953-1961
[8]
Use of oral prednisolone or naproxen for the treatment of gout arthritis: a double-blind, randomised equivalence trial [J].
Janssens, Hein J. E. M. ;
Janssen, Matthijs ;
van de Lisdonk, Eloy H. ;
van Riel, Piet L. C. M. ;
van Weel, Chris .
LANCET, 2008, 371 (9627) :1854-1860
[9]
Comparison of oral prednisolone/paracetamol and oral indomethacin/paracetamol combination therapy in the treatment of acute goutlike arthritis: A double-blind, randomized, controlled trial [J].
Man, Chi Yin ;
Cheung, Ian T. F. ;
Cameron, Peter A. ;
Rainer, Timothy H. .
ANNALS OF EMERGENCY MEDICINE, 2007, 49 (05) :670-677
[10]
Uric acid nephrolithiasis.[J].Scott E. Liebman;Jeremy G. Taylor;David A. Bushinsky.Current Rheumatology Reports.2007, 3