增生性瘢痕和瘢痕疙瘩的最新治疗进展

被引:47
作者
马倩玉
武晓莉
机构
[1] 上海交通大学医学院附属第九人民医院整复外科
关键词
病理性瘢痕; 增生性瘢痕; 瘢痕疙瘩; 治疗;
D O I
暂无
中图分类号
R622 [整形手术学];
学科分类号
100224 [整形外科学];
摘要
病理性瘢痕是创伤后皮肤组织过度增生的结果,常见的致病因素包括外伤、烧伤、手术、疫苗接种、皮肤穿刺、痤疮和带状疱疹等,但具体发病机制仍未完全阐明。病理性瘢痕可对患者的生理功能和心理健康造成不良影响。传统的治疗手段包括压迫治疗、硅胶制剂、药物治疗、手术、放射治疗等,新的治疗方法包括激光、自体脂肪移植、免疫疗法、基因疗法等,但尚未有令人满意的单一疗法,因此综合治疗仍是目前临床的首选。
引用
收藏
页码:1 / 5+26 +26
页数:6
相关论文
共 19 条
[1]
The Effect of Chyle Fat Injection on Human Hypertrophic Scars in an Animal Model: A New Strategy for the Treatment of Hypertrophic Scars.[J].Junnan Chen;Linying Lai;Kui Ma;Xiao Xu;Zhenya Huang;Guiwen Zhou;Yunchao Zhou;Liming Liang;Minliang Chen.Annals of Plastic Surgery.2019,
[2]
Efficacy of 5-aminolevulinic acid–based photodynamic therapy against keloid compromised by downregulation of SIRT1-SIRT3-SOD2-mROS dependent autophagy pathway.[J].Tao Liu;Xiaorong Ma;Tianxiang Ouyang;Huiping Chen;Yan Xiao;Yingying Huang;Jun Liu;Miao Xu.Redox Biology.2018,
[3]
Current and upcoming therapies to modulate skin scarring and fibrosis.[J].João Q. Coentro;Eugenia Pugliese;Geoffrey Hanley;Michael Raghunath;Dimitrios I. Zeugolis.Advanced Drug Delivery Reviews.2019,
[4]
Efficacy and the toxicity of the interstitial high-dose-rate brachytherapy in the management of recurrent keloids: 5-year outcomes [J].
Jiang, Ping ;
Geenen, Matthias ;
Siebert, Frank-Andre ;
Bertolini, Julia ;
Poppe, Bjoern ;
Luetzen, Ulf ;
Dunst, Juergen ;
Druecke, Daniel .
BRACHYTHERAPY, 2018, 17 (03) :597-600
[5]
Comparison of the effectiveness of pulsed dye laser vs pulsed dye laser combined with ultrapulse fractional CO <sub>2</sub> laser in the treatment of immature red hypertrophic scars.[J].Hua‐wei Ouyang MD;Gao‐feng Li MD;Ying Lei MD;Michael H Gold MD;Jun Tan MD.Journal of Cosmetic Dermatology.2018, 1
[6]
Treatment of keloid scars using light-, laser- and energy-based devices: a contemporary review of the literature [J].
Forbat, E. ;
Ali, F. R. ;
Al-Niaimi, F. .
LASERS IN MEDICAL SCIENCE, 2017, 32 (09) :2145-2154
[7]
Clinical efficacy of utilizing Ultrapulse CO <sub>2</sub> combined with fractional CO <sub>2</sub> laser for the treatment of hypertrophic scars in Asians—A prospective clinical evaluation.[J].Ying Lei MD;Shi Feng Li MD;Yi Ling Yu;Jun Tan MD;Michael H. Gold MD.Journal of Cosmetic Dermatology.2017, 2
[8]
Fat Grafting for Burn, Traumatic, and Surgical Scars [J].
Fredman, Rafi ;
Katz, Adam J. ;
Hultman, Charles Scott .
CLINICS IN PLASTIC SURGERY, 2017, 44 (04) :781-+
[9]
Efficacy and safety of triamcinolone acetonide alone and in combination with 5-fluorouracil for treating hypertrophic scars and keloids: a systematic review and meta-analysis [J].
Ren, YiMing ;
Zhou, XianHu ;
Wei, ZhiJian ;
Lin, Wei ;
Fan, BaoYou ;
Feng, ShiQing .
INTERNATIONAL WOUND JOURNAL, 2017, 14 (03) :480-487
[10]
The Use of Autologous Fat Grafting for Treatment of Scar Tissue and Scar-Related Conditions: A Systematic Review [J].
Negenborn, Vera L. ;
Groen, Jan-Willem ;
Smit, Jan Maerten ;
Niessen, Frank B. ;
Mullender, Margriet G. .
PLASTIC AND RECONSTRUCTIVE SURGERY, 2016, 137 (01) :31E-43E