建立中医药临床研究核心结局指标集

被引:47
作者
于长禾 [1 ]
孙亚男 [2 ]
何丽云 [1 ]
范吉平 [1 ]
机构
[1] 中国中医科学院
[2] 首都医科大学宣武医院
关键词
核心结局指标集; 测量工具; 测量时间框架; 中医; 临床研究;
D O I
暂无
中图分类号
R241 [中医诊断学];
学科分类号
100505 [中医诊断学];
摘要
中医药系统评价和Meta分析研究表明现有中医临床研究存在以下问题:选择疗效结局不公认,设计结局及其指标广泛且不统一,存在选择性报告偏倚的风险高,研究缺失数据多等。建立必须报告的、统一的、公认的、标准化的结局指标最小集合,即核心结局指标集(COS),不仅可以降低选择性报告偏倚,而且可以使相同干预措施的临床研究进行Meta分析或者不同干预措施的研究进行横向比较,方便临床医生选择更适合患者的治疗方法,文章将对COS的概念和研究方法进行描述。
引用
收藏
页码:2526 / 2529
页数:4
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