共 9 条
[1]
Potential role of intestinal first-pass metabolism in the prediction of drug–drug interactions[J] Galetin;Gertz;Houston Expert Opinion on Drug Metabolism & Toxicology 2008,
[2]
In Vitro Evaluation of Reversible and Irreversible Cytochrome P450 Inhibition: Current Status on Methodologies and their Utility for Predicting Drug–Drug Interactions[J] Stephen Fowler;Hongjian Zhang The AAPS Journal 2008,
[3]
Primary Hepatocytes: Current Understanding of the Regulation of Metabolic Enzymes and Transporter Proteins; and Pharmaceutical Practice for the Use of Hepatocytes in Metabolism; Enzyme Induction; Transporter; Clearance; and Hepatotoxicity Studies[J] Nicola J. Hewitt;María José Gómez Lechón;J. Brian Houston;David Hallifax;Hayley S. Brown;Patrick Maurel;J. Gerald Kenna;Lena Gustavsson;Christina Lohmann;Christian Skonberg;Andre Guillouzo;Gregor Tuschl;Albert P. Li;Edward
[4]
Comparison of different approaches to predict metabolic drug–drug interactions[J] H. J. Einolf Xenobiotica 2007,
[5]
Prediction of in vivo drug–drug interactions from in vitro data: impact of incorporating parallel pathways of drug elimination and inhibitor absorption rate constant[J] Hayley S.Brown;KiyomiIto;AleksandraGaletin;J. BrianHouston British Journal of Clinical Pharmacology 2005,
[6]
A human and mouse pregnane X receptor reporter gene assay in combination with cytotoxicity measurements as a tool to evaluate species-specific CYP3A induction[J] Luisella A Vignati;Alessia Bogni;Pietro Grossi;Mario Monshouwer Toxicology 2004,
[7]
The Intestinal First-pass Metabolism of Substrates of CYP3A4 and P-glycoprotei—Quantitative Analysis Based on Information from the Literature[J] Motohiro Kato;Koji Chiba;Akihiro Hisaka;Michi Ishigami;Makoto Kayama;Naomi Mizuno;Yoshinori Nagata;Susumu Takakuwa;Yuko Tsukamoto;Kaoru Ueda;Hiroyuki Kusuhara;Kiyomi Ito;Yuichi Sugiyama Drug Metabolism and Pharmacokinetics 2003,
[8]
Human Drug Metabolism and the Cytochromes P450: Application and Relevance of In Vitro Models[J] Karthik Venkatakrishnan;Lisa L. von Moltke;David J. Greenblatt The Journal of Clinical Pharmacology 2001,
[9]
Use of the nuclear receptor PXR to predict drug interactions[J] John T. Moore;Steven A. Kliewer Toxicology 2000,