脑-肠轴失调在肠易激综合征发病中作用的研究进展

被引：17

作者：

张磊

宋军

侯晓华

机构：

[1] 华中科技大学同济医学院附属协和医院消化科

来源：

胃肠病学 | 2014年 / 19卷 / 11期

关键词：

肠易激综合征; 脑-肠轴; 神经分泌系统; 应激;

D O I：

暂无

中图分类号：

R574 [肠疾病];

学科分类号：

1002 ; 100201 ;

摘要：

肠易激综合征(IBS)的发生是多因素共同作用的结果,其发病机制尚未明确。近年来,以脑-肠轴为基础的生物-心理-社会医学模式参与IBS发病的观念被广泛接受。由神经-内分泌-免疫网络介导的脑-肠双向调节通路,在维持中枢神经系统与肠道局部稳态中发挥重要调节作用,其中任一环节异常,都可能导致稳态平衡破坏而诱发IBS。本文就脑-肠轴失调在IBS发生、发展中作用的研究进展作一综述。

引用

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页码：688 / 691

页数：4

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