幽门螺杆菌在胃食管反流病中的作用

被引：9

作者：

刘燕

于晓峰

宓林

机构：

[1] 复旦大学附属华东医院消化科

来源：

胃肠病学和肝病学杂志 | 2015年 / 24卷 / 07期

关键词：

胃食管反流病; 幽门螺杆菌;

D O I：

暂无

中图分类号：

R571 [食管疾病];

学科分类号：

100201 [内科学];

摘要：

目的探讨幽门螺杆菌(H.pylori)感染与胃食管反流病(gastroesophageal reflux disease,GERD)的关系。方法收集并前瞻性分析2013年1月-2014年1月在复旦大学附属华东医院内镜室行胃镜检查的患者,纳入GERD患者984例及慢性浅表性胃炎患者2 136例,两组均行快速尿素酶试验进行H.pylori检测,对比两组H.pylori感染情况;将984例GERD患者分为NERD、RE-A、B组及RE-C、D组,对比三组H.pylori感染情况;随机选取60例H.pylori(+)GERD患者,均采用标准四联方案,其中54例成功根治H.pylori后的GERD患者继续随访3个月了解患者症状变化。结果 GERD组H.pylori感染的阳性率(35.98%)低于对照组(36.99%),但差异无统计学意义(P>0.05)。NERD组、RE-A、B组和RE-C、D组H.pylori感染率分别是36.19%、35.58%、35.96%,三组之间差异无统计学意义(P>0.05)。54例成功根除H.pylori的GERD患者随访3个月患者症状无明显改善。结论H.pylori感染与GERD之间无明显相关性,且H.pylori阳性GERD患者行H.pylori根治后症状无明显改善。

引用

页码：807 / 809

页数：3

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