强骨胶囊联合鲑鱼降钙素针剂治疗对老年骨质疏松性压缩骨折患者骨密度及骨代谢的影响

被引：23

作者：

黎立

司裕

机构：

[1] 新疆医科大学附属中医医院骨三科

来源：

海南医学院学报 | 2016年 / 22卷 / 16期

关键词：

老年骨质疏松性压缩骨折; 强骨胶囊; 鲑鱼降钙素针剂; 骨代谢;

D O I：

10.13210/j.cnki.jhmu.20160513.003

中图分类号：

R580 []; R683 [骨折、骨的损伤];

学科分类号：

100220 [骨科学];

摘要：

目的:分析强骨胶囊联合鲑鱼降钙素针剂治疗对老年骨质疏松性压缩骨折患者骨密度及骨代谢的影响。方法:92例老年骨质疏松性压缩骨折患者按照随机数表法分为观察组及对照组,各46例,对照组接受单独强骨胶囊治疗,观察组接受强骨胶囊联合鲑鱼降钙素针剂治疗,对比两组骨密度、骨代谢指标及CT相关参数差异。结果:观察组治疗3个疗程及6个疗程后骨密度(BMD)值高于对照组(P<0.05);观察组治疗后血清骨钙素(BGP)、甲状旁腺激素(PTH)值高于对照组,Ⅰ型胶原羧基端前肽(CICP)、Ⅰ型胶原羧基端交联肽(CTX-Ⅰ)值低于对照组,尿液中脱氧胶原吡啶交联(D-Pyr)值低于对照组(P<0.05);观察组治疗后松质骨体积(CV)、CV/MV值高于对照组,髓腔体积(MV)值低于对照组(P<0.05)。结论:强骨胶囊联合鲑鱼降钙素针剂可以抑制老年骨质疏松性压缩骨折患者病情进展,优化骨代谢过程并促进成骨过程,具有积极的临床意义。

引用

页码：1809 / 1811+1815 +1815

页数：4

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