小胶质细胞介导的免疫损伤在帕金森病中的作用

被引：1

作者：

李锐

杜芳

机构：

[1] 中科院上海生命科学研究院健康科学中心

来源：

国外医学神经病学神经外科学分册 | 2003年 / 05期

关键词：

帕金森病; 小胶质细胞; 细胞因子; 自由基;

D O I：

10.16636/j.cnki.jinn.2003.05.027

中图分类号：

R742.5 [震颤麻痹综合征];

学科分类号：

1002 ;

摘要：

慢性炎症反应介导的免疫损伤在帕金森病等中枢神经变性疾病中扮演重要的角色,在此过程中,各种原因作用下小胶质细胞的激活所产生的前炎症细胞因子和自由基启动或加重了多巴胺能神经元的损伤。以抑制小胶质细胞激活为靶向的治疗方法将为帕金森病等神经变性疾病的治疗提供新的思路。

引用

页码：486 / 489

页数：4

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