3种寡核苷酸探针对龈下菌斑中牙周致病菌的检测附视频

被引：5

作者：

张贤华

张斌

吴织芬

机构：

[1] 四川大学华西口腔医院牙周科

[2] 第四军医大学基础部生物化学与分子生物学教研室

[3] 第四军医大学口腔医院牙周科

来源：

华西口腔医学杂志 | 2003年 / 04期

关键词：

牙周炎; 牙龈卟啉单胞菌; 福赛类杆菌; 牙密螺旋体; 寡核苷酸探针;

D O I：

暂无

中图分类号：

R781.4 [牙周病];

学科分类号：

摘要：

目的　采用寡核苷酸探针研究龈下菌斑中 3种牙周致病菌的分布。方法　利用 3种寡核苷酸探针对6 0例慢性牙周炎患者 6 0个患病位点、10例健康人的 10个健康对照位点龈下菌斑中的牙龈卟啉单胞菌、福赛类杆菌、牙密螺旋体进行检测。结果　牙周炎位点龈下菌斑中的牙龈卟啉单胞菌、福赛类杆菌、牙密螺旋体的检出率分别为 91 6 7%,90 0 0 %和 95 6 7%,明显高于健康对照位点 ;有 83 33%的牙周炎位点同时检出 3种致病菌 ,3种细菌检出情况为两两正相关 (P <0 0 1)。结论　牙龈卟啉单胞菌、福赛类杆菌、牙密螺旋体在慢性牙周炎患者龈下菌斑中的检出率很高 ,它们间可能存在相互协同致病作用。

引用

页码：287 / 288+310 +310

页数：3

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