免疫抑制剂在狼疮性肾炎治疗中的应用

被引:7
作者
于峰
赵明辉
机构
[1] 北京大学第一医院肾内科北京大学肾脏病研究所
关键词
狼疮性肾炎; 免疫抑制剂;
D O I
暂无
中图分类号
R593.242 [];
学科分类号
1002 ; 100201 ;
摘要
狼疮性肾炎是系统性红斑狼疮较常见且严重的并发症,其治疗原则应包括免疫抑制治疗和支持治疗。免疫抑制治疗的强度应根据临床和肾脏病理的活动度来确定。狼疮性肾炎治疗的最终目标是防止狼疮性肾炎复发,保护肾功能。诱导缓解阶段应力争达到完全缓解,维持缓解期应坚持长期治疗,应注意个体化治疗,并随时警惕治疗药物的副反应。
引用
收藏
页码:498 / 500
页数:3
相关论文
共 7 条
[1]  
Beyond immunosuppression-challen-ges in the clinical management of lupus nephritis. Masood S,Jayne D,Karim Y. Lupus . 2009
[2]  
Induction treatment of pro-liferative lupus nephritis with leflunomide combined with predni-sone:a prospective multicentre observational study. Wang H Y,,Gui T G,Hou F F,et al. Lupus . 2008
[3]  
Update on immunotherapy for systemic lupus erythematosus—what s hot and what s not!. Karim MY,Pisoni CN,Khamashta MA. Rheumatology . 2009
[4]  
The10-year follow-up data of the Euro-Lupus Nephritis Trial comparing low-dose ver-sus high-dose intravenous cyclophosphamide. Houssiau FA,Vasconcelos C,D Cruz D,et al. Annals of the Rheumatic Diseases . 2009
[5]  
Pharmacokinetics of mycophenolic acid in patients with lupus nephritis. Joy MS,Hilliard T,Hu Y,et al. Pharmacotherapy . 2009
[6]  
Rituximab and mycophe-nolate mofetil for relapsing proliferative lupus nephritis:a long-term prospective study. Boletis JN,Marinaki S,Skalioti C,et al. Nephrology Dialysis Transplantation . 2009
[7]  
Successful treatment of classⅤ+Ⅳlupus nephritis with multitarget therapy. Bao H,Liu ZH,Xie HL,et al. Journal of the American Society of Nephrology . 2008