丝裂霉素C诱发小鼠胎肝及胎血多染红细胞内微核与母鼠骨髓及外周血微核之比较

被引:1
作者
冯静仪
张玉华
凌宝银
刘杰
机构
[1] 江苏省卫生防疫站毒理室
关键词
微核率; 胎血; 胎肝; 母鼠; 细胞内; 外周血; 小鼠; 小家鼠; 丝裂霉素; 抗癌抗菌素;
D O I
暂无
中图分类号
学科分类号
摘要
<正> 微核试验预测染色体损伤之报道甚多,Schmid首先提出骨髓染色体断裂及纺缍损伤是微核形成的基础,并指出它能正确地反映染色体损伤效应。Cole等1979年又提出胎肝及胎血嗜多染红细胞微核试验可作为评价化
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页码:158 / 161
页数:4
相关论文
共 8 条
[1]  
Micronucleus formation in foelal and materal mouse erythroblasts. Cole RJ, et al. Mutation Research . 1981
[2]  
Transplacental effects of chemical mutagens detacted by the micronucleus test. Cole RJ and Cole J. Nature . 1979
[3]  
Multiple dose regimes in the transplacental micronucleus. Cole RJ, et al. Mutation Research . 1982
[4]  
The micronucleus test. Schmid Bp et al. Mutation Research . 1975
[5]  
A comparison of sister-chromatid exchange and the micronucleus test in mouse faetal liver erythroblasts. Cole RJ, et al. Mutation Research . 1983
[6]  
The persistence of micronucleus in peripheral blood erythrocytes: Detection of chronic chromosome breakage in mice. Robert Schleget and Jame T. Mutation Research . 1982
[7]  
A rapid screen for cummlative chromosomal damage in mice.Accumulation of circulating micronucleated erythrocytes. Robert Schleget,et al. Mutation Research . 1983
[8]  
Induction of SCE in faetal brain, lung and blood-forming cells by procarbazine and cyclophosphamide. Cole RJ, et al. Mutation Research . 1982