外用吡啶酮酸类化学抗菌药物对烧伤后绿脓杆菌感染的防治功效

被引:6
作者
葛绳德 [1 ]
霍正录 [1 ]
胡云风 [1 ]
方之杨 [1 ]
黄月仙 [2 ]
凌代文 [2 ]
屠世忠 [3 ]
蒋雪涛 [3 ]
李全 [3 ]
郑友 [4 ]
施琦云 [4 ]
机构
[1] 第二军医大学
关键词
绿脓杆菌; 防治实验; 未定型; 银盐; 极毛杆菌属; 抗菌药物; 吡啶酮; 酸类;
D O I
暂无
中图分类号
R644 [烧伤及烫伤(灼伤)]; R446.5 [微生物学检验];
学科分类号
摘要
本研究以吡啶酮酸类第二代和第三代产品的银盐与磺胺嘧啶银对比, 对具有血清多凝性未定型的绿脓杆菌进行药物敏感度测定。并以各药的霜剂, 在以基础霜剂为对照下, 对小鼠尾和大白兔背烫伤后绿脓杆菌感染作防治实验。结果示氟哌酸银是强有力的化学抗菌药物, 特别对针对磺胺嘧啶银有一定程度耐药的未定型绿脓杆菌菌株引起的烧伤局部感染具有较强的防治功效。其作用和疗效超过吡哌酸银。
引用
收藏
页码:10 / 13
页数:4
相关论文
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