肺癌脑转移与血清肿瘤标志物变化的相关性

被引：11

作者：

符琳琳 ^{[1
,2
]}

机构：

[1] 中国人民解放军总医院老年病学科

[2] 首都医科大学附属复兴医院

来源：

现代肿瘤医学 | 2017年 / 25卷 / 13期

关键词：

肺癌脑转移; 血清肿瘤标志物; 相关性;

D O I：

暂无

中图分类号：

R734.2 [肺肿瘤];

学科分类号：

100117 [系统生物医学];

摘要：

目的:观察肺癌脑转移与血清肿瘤标志物变化的相关性。方法:回顾性分析2010年2月至2015年124例肺癌患者临床资料,其中45例脑转移和同时期101例健康体检者(健康对照组)血清肿瘤标志物指标进行比较。结果:肺癌肿瘤标志物指标AFP、CEA、NSE、CA125、CYFRA21-1、SCC-Ag含量水平均显著高于健康对照组(P<0.05)。肺癌脑转移和CEA、CYFRA21-1、SCC-Ag升高,分化程度低,淋巴结转移有关(P<0.05),而和性别、年龄、吸烟史、AFP、NSE、CA125、病理类型无关(P>0.05);其中CYFRA21-1、CEA、SCC-Ag升高、分化程度、淋巴结转移是肺癌脑转移独立危险因素(P均<0.05)。结论:血清肿瘤标志物CYFRA21-1、CEA、SCC-Ag是肺癌脑转移独立危险因素,在临床上要注重检测以上肿瘤标志物。

引用

收藏

页码：2071 / 2074

页数：4

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