高尿酸血症与慢性肾脏病关系的研究进展

被引：21

作者：

曾楚楚 ^{[1
]}

范瑛 ^{[2
]}

汪年松 ^{[2
]}

机构：

[1] 苏州大学

[2] 上海交通大学附属第六人民医院肾脏科

来源：

中国中西医结合肾病杂志 | 2016年 / 17卷 / 02期

关键词：

D O I：

暂无

中图分类号：

R692 [肾疾病]; R589.7 [嘌呤（Purine）代谢障碍];

学科分类号：

100201 [内科学]; 100221 [泌尿外科学];

摘要：

<正>近年来,高尿酸血症(hyperuricemia,HUA)与慢性肾脏病(chronic kidney disease,CKD)之间的关系已成为国内外研究热点。随着人们饮食结构和生活方式的改变,HUA的发病率在逐年增加,已经成为威胁人类健康的代谢性疾病之一。HUA不仅是痛风的主要原因,血尿酸水平的升高也不仅仅是肾功能减退的指标,近年来越来越多的研究发现HUA在CKD的发生

引用

页码：167 / 169

页数：3

共 13 条

[1]

Allopurinol and Progression of CKD and Cardiovascular Events: Long-term Follow-up of a Randomized Clinical Trial [J].

Goicoechea, Marian ;

Garcia de Vinuesa, Soledad ;

Verdalles, Ursula ;

Verde, Eduardo ;

Macias, Nicolas ;

Santos, Alba ;

Perez de Jose, Ana ;

Cedeno, Santiago ;

Linares, Tania ;

Luno, Jose .

AMERICAN JOURNAL OF KIDNEY DISEASES, 2015, 65 (04) :543-549

[2]

Comorbidities of Gout and Hyperuricemia in the US General Population: NHANES 2007-2008 [J].

Zhu, Yanyan ;

Pandya, Bhavik J. ;

Choi, Hyon K. .

AMERICAN JOURNAL OF MEDICINE, 2012, 125 (07) :679-+

[3]

New Insights into Uric Acid Effects on the Progression and Prognosis of Chronic Kidney Disease [J].

Filiopoulos, Vassilis ;

Hadjiyannakos, Dimitrios ;

Vlassopoulos, Dimosthenis .

RENAL FAILURE, 2012, 34 (04) :510-520

[4]

Serum Uric Acid Levels and Incident Chronic Kidney Disease in Patients With Type 2 Diabetes and Preserved Kidney Function [J].

Zoppini, Giacomo ;

Targher, Giovanni ;

Chonchol, Michel ;

Ortalda, Vittorio ;

Abaterusso, Cataldo ;

Pichiri, Isabella ;

Negri, Carlo ;

Bonora, Enzo .

DIABETES CARE, 2012, 35 (01) :99-104

[5]

Effect of a Reduction in Uric Acid on Renal Outcomes During Losartan Treatment A Post Hoc Analysis of the Reduction of Endpoints in Non-Insulin-Dependent Diabetes Mellitus With the Angiotensin II Antagonist Losartan Trial [J].

Miao, Yan ;

Ottenbros, Stefan A. ;

Laverman, Goos D. ;

Brenner, Barry M. ;

Cooper, Mark E. ;

Parving, Hans-Henrik ;

Grobbee, Diederick E. ;

Shahinfar, Shahnaz ;

de Zeeuw, Dick ;

Lambers Heerspink, Hiddo J. .

HYPERTENSION, 2011, 58 (01) :2-7

[6]

Uric Acid Levels Predict Future Development of Chronic Kidney Disease [J].

Sonoda, Hiroo ;

Takase, Hiroyuki ;

Dohi, Yasuaki ;

Kimura, Genjiro .

AMERICAN JOURNAL OF NEPHROLOGY, 2011, 33 (04) :352-357

[7]

Relationship between serum uric acid levels with chronic kidney disease in a Southeast Asian population [J].

Satirapoj, Bancha ;

Supasyndh, Ouppatham ;

Chaiprasert, Amnart ;

Ruangkanchanasetr, Prajej ;

Kanjanakul, Inseey ;

Phulsuksombuti, Duangporn ;

Utainam, Darunee ;

Choovichian, Panbuppa .

NEPHROLOGY, 2010, 15 (02) :253-258

[8]

Uric Acid and Long-term Outcomes in CKD [J].

Madero, Magdalena ;

Sarnak, Mark J. ;

Wang, Xuelei ;

Greene, Tom ;

Beck, Gerald J. ;

Kusek, John W. ;

Collins, Allan J. ;

Levey, Andrew S. ;

Menon, Vandana .

AMERICAN JOURNAL OF KIDNEY DISEASES, 2009, 53 (05) :796-803

[9]

Uric acid stimulates vascular smooth muscle cell proliferation and oxidative stress via the vascular renin–angiotensin system.[J].Dalila B Corry;Pirooz Eslami;Kei Yamamoto;Michael D Nyby;Hirofumi Makino;Michael L Tuck.Journal of Hypertension.2008, 2

[10]

Effect of treatment of hyperuricemia with allopurinol on blood pressure, creatinine clearence, and proteinuria in patients with normal renal functions [J].

Kanbay, Mehmet ;

Ozkara, Adem ;

Selcoki, Yusuf ;

Isik, Bunyamin ;

Turgut, Faruk ;

Bavbek, Nuket ;

Uz, Ebru ;

Akcay, Ali ;

Yigitoglu, Ramazan ;

Covic, Adrian .

INTERNATIONAL UROLOGY AND NEPHROLOGY, 2007, 39 (04) :1227-1233

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