北京高龄老年男性骨骼肌含量减少与行走功能的相关性研究

被引：11

作者：

张颖 ^{[1
]}

胡亦新 ^{[2
]}

范利 ^{[2
]}

张曼秀 ^{[2
]}

孙静 ^{[2
]}

韩晓琦 ^{[2
]}

马晓娜 ^{[2
]}

董宏艳 ^{[3
]}

李梅 ^{[4
]}

机构：

[1] 解放军总医院南楼骨密度室

[2] 解放军总医院南楼保健科

[3] 解放军第医院干部病房

[4] 解放军总装备部后勤部保健局

来源：

中华保健医学杂志 | 2014年 / 16卷 / 06期

关键词：

老年肌少症; 步速; 骨骼肌; 功能; 高龄;

D O I：

暂无

中图分类号：

R592 [老年病学];

学科分类号：

100201 [内科学];

摘要：

目的调查北京某社区80岁以上老年男性增龄性骨骼肌减少的患病率,探讨不同部位骨骼肌含量、体脂含量与行走功能改变的关系。方法 2013年2月2014年5月随机选取116名80岁以上在门诊体检的北京社区退休老年人和85名20～40岁的健康志愿者,使用双光能X线骨密度仪测量骨骼肌含量,检测6米步行速度及握力。结果 80岁以上男性肌少症前期、肌少症、严重肌少症的检出率分别为12.1%、21.2%、20.2%;老年肌少症组体重、握力、步速、下肢骨骼肌含量、四肢骨骼肌含量、相对骨骼肌指数（RASM）均显著低于非肌少症组（P<0.05）,下肢脂肪含量、总体脂肪含量在两组之间无显著差异;步速与大腿骨骼肌含量（r=0.246,P=0.036）呈正相关,与年龄（r=-0.253,P=0.030）、上肢脂肪含量（r=-0.358,P=0.043）、大腿脂肪含量（r=-0.285,P=0.018）、躯干脂肪含量（r=-0.253,P=0.037）、全身脂肪含量（r=-0.281,P=0.015）、总体脂肪百分比（r=-0.345,P=0.002）呈负相关;多元线性回归分析显示,大腿骨骼肌含量（β=0.232,P=0.016）与步速呈正相关,年龄（β=-0.532,P=0.000）、总体脂肪含量（β=-0.217,P=0.002）与步速独立负相关。结论根据EWGSOP标准,北京地区高龄老年肌少症的患病率较高,大腿骨骼肌含量与步速正相关,年龄、总体脂肪含量与步速负相关。在高龄老年肌少症与机体功能的研究中,除了开展改善下肢骨骼肌肌力、肌量的研究,还应关注体脂含量对躯体功能影响的研究。

引用

页码：421 / 425

页数：5

共 9 条

[1]

A cross-sectional study of loss of muscle mass corresponding to sarcopenia in healthy Chinese men and women: reference values, prevalence, and association with bone mass [J].

Cheng, Qun ;

Zhu, Xiaoying ;

Zhang, Xuemei ;

Li, Huilin ;

Du, Yanping ;

Hong, Wei ;

Xue, Sihong ;

Zhu, Hanmin .

JOURNAL OF BONE AND MINERAL METABOLISM, 2014, 32 (01) :78-88

[2]

Comparisons of Sarcopenia Defined by IWGS and EWGSOP Criteria Among Older People: Results From the I-Lan Longitudinal Aging Study [J].

Lee, Wei-Ju ;

Liu, Li-Kuo ;

Peng, Li-Ning ;

Lin, Ming-Hsien ;

Chen, Liang-Kung .

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2013, 14 (07) :528-+

[3]

Prevalence of Sarcopenia and Sarcopenic Obesity in the Korean Population Based on the Fourth Korean National Health and Nutritional Examination Surveys [J].

Kim, Young-Sang ;

Lee, Yunhwan ;

Chung, Yoon-Sok ;

Lee, Duck-Joo ;

Joo, Nam-Seok ;

Hong, Doohee ;

Song, Go Eun ;

Kim, Hyeon-Jeong ;

Choi, Yong Jun ;

Kim, Kwang-Min .

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2012, 67 (10) :1107-1113

[4]

Association between sarcopenia and higher-level functional capacity in daily living in community-dwelling elderly subjects in Japan [J].

Tanimoto, Yoshimi ;

Watanabe, Misuzu ;

Sun, Wei ;

Sugiura, Yumiko ;

Tsuda, Yuko ;

Kimura, Motoshi ;

Hayashida, Itsushi ;

Kusabiraki, Toshiyuki ;

Kono, Koichi .

ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2012, 55 (02) :E9-E13

[5]

Relationship between site-specific loss of thigh muscle and gait performance in women: The HIREGASAKI study [J].

Abe, Takashi ;

Ogawa, Madoka ;

Loenneke, Jeremy P. ;

Thiebaud, Robert S. ;

Loftin, Mark ;

Mitsukawa, Naotoshi .

ARCHIVES OF GERONTOLOGY AND GERIATRICS, 2012, 55 (02) :E21-E25

[6]

Sarcopenia: An Undiagnosed Condition in Older Adults. Current Consensus Definition: Prevalence, Etiology, and Consequences. International Working Group on Sarcopenia [J].

Fielding, Roger A. ;

Vellas, Bruno ;

Evans, William J. ;

Bhasin, Shalender ;

Morley, John E. ;

Newman, Anne B. ;

van Kan, Gabor Abelian ;

Andrieu, Sandrine ;

Bauer, Juergen ;

Breuille, Denis ;

Cederholm, Tommy ;

Chandler, Julie ;

De Meynard, Capucine ;

Donini, Lorenzo ;

Harris, Tamara ;

Kannt, Aimo ;

Guibert, Florence Keime ;

Onder, Graziano ;

Papanicolaou, Dimitris ;

Rolland, Yves ;

Rooks, Daniel ;

Sieber, Cornet ;

Souhami, Elisabeth ;

Verlaan, Sjors ;

Zamboni, Mauro .

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2011, 12 (04) :249-256

[7]

Poor physical function in elderly women in low-level aged care is related to muscle strength rather than to measures of sarcopenia.[J].Karen Walker;Boyd Strauss;Susannah King;Sandra Luliano-Burns;Woods.Clinical Interventions in Aging.2011, defa

[8]

Quadriceps sarcopenia and visceral obesity are risk factors for postural instability in the middle-aged to elderly population [J].